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经肛门全直肠系膜切除术与腹腔镜经腹全直肠系膜切除术治疗低位直肠癌的单中心回顾性病例对照研究

Simple transanal total mesorectal resection versus laparoscopic transabdominal total mesorectal resection for the treatment of low rectal cancer: a single-center retrospective case-control study.

作者信息

Yang Wei-Feng, Chen Wenbin, He Zijian, Wu Zixin, Liu Huilong, Li Guanwei, Li Wang-Lin

机构信息

School of Medicine, South China University of Technology, Guangzhou, China.

出版信息

Front Surg. 2023 Jul 27;10:1171382. doi: 10.3389/fsurg.2023.1171382. eCollection 2023.

Abstract

AIM

To evaluate the efficacy and safety of simple TaTNE in the treatment of low rectal cancer compared with laparoscopic transabdominal TME.

METHODS

We collected patients with low rectal cancer admitted to our hospital between January 2019 and November 2021 who received simple TaTME or laparoscopic transabdominal TME. The main outcome was the integrity of the TME specimen. Secondary outcomes were the number of lymph nodes dissected, intraoperative blood loss, operative time, surgical conversion rate, Specimen resection length, circumferential margin (CRM), and distal resection margin (DRM), complication rate. In addition, the Wexner score and LARS score of fecal incontinence were performed in postoperative follow-up.

RESULTS

Pathological tissues were successfully resected in all patients. all circumferential margins of the specimen were negative. Specimen resection length was not statistically significant (9.94 ± 2.85 vs. 8.90 ± 2.49,  > 0.05). The incidence of postoperative complications in group A ( = 0) was significantly lower than that in group B ( = 3) ( > 0.05). There was no significant difference in operation time between group A and group B (296 ± 60.36 vs. 305 ± 58.28,  > 0.05). Among the patients with follow-up time less than 1 year, there was no significant difference in Wexner score and LARS score between group A and group B ( > 0.05). However, in patients who were followed up for more than 1 year, the Wexner score in group A (9.25 ± 2.73) was significantly lower than that in group B (17.36 ± 10.95) and was statistically significant ( < 0.05).

CONCLUSION

For radical resection of low rectal cancer, Simple TaTME resection may be as safe and effective as laparoscopic transabdominal TME, and the long-term prognosis may be better.

摘要

目的

评估单纯经肛门全直肠系膜切除术(TaTME)与腹腔镜经腹全直肠系膜切除术(TME)治疗低位直肠癌的疗效和安全性。

方法

收集2019年1月至2021年11月在我院接受单纯TaTME或腹腔镜经腹TME的低位直肠癌患者。主要结局是TME标本的完整性。次要结局包括清扫淋巴结数量、术中出血量、手术时间、手术中转率、标本切除长度、环周切缘(CRM)、远切缘(DRM)及并发症发生率。此外,术后随访时进行大便失禁的Wexner评分和LARS评分。

结果

所有患者均成功切除病理组织。标本的所有环周切缘均为阴性。标本切除长度差异无统计学意义(9.94±2.85 vs. 8.90±2.49,P>0.05)。A组术后并发症发生率(=0)显著低于B组(=3)(P>0.05)。A组和B组手术时间差异无统计学意义(296±60.36 vs. 305±58.28,P>0.05)。随访时间小于1年的患者中,A组和B组的Wexner评分和LARS评分差异无统计学意义(P>0.05)。然而,在随访超过1年的患者中,A组的Wexner评分(9.25±2.73)显著低于B组(17.36±10.95),差异有统计学意义(P<0.05)。

结论

对于低位直肠癌的根治性切除,单纯TaTME切除可能与腹腔镜经腹TME一样安全有效,且长期预后可能更好。

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[Controversy and prospect of transanal total mesorectal excision].经肛门全直肠系膜切除术的争议与展望
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