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经肛门全直肠系膜切除术的争议与展望

[Controversy and prospect of transanal total mesorectal excision].

作者信息

Li L, Long F, Lin C W, Ma M, Hu G, Zhang Y

机构信息

Department of Gastrointestinal Surgery, the Third Xiangya Hospital, Central South University, Changsha 410013, China.

出版信息

Zhonghua Wei Chang Wai Ke Za Zhi. 2021 Aug 25;24(8):727-734. doi: 10.3760/cma.j.cn.441530-20200929-00545.

Abstract

As a novel surgical technique, taTME has developed rapidly in recent years. TaTME inevitably attracts some skepticism on safety, efficacy, and indication. First, the controversies over taTME are mainly reflected on the safety and effectiveness of taTME. On one hand, the increase of surgical complications, such as urethral injury, CO2 embolism, anastomotic leakage and pelvic infection, has raised concerns about the safety of taTME. Second, the poor quality of taTME specimens, the increased local recurrence rate and the impaired anal function after taTME, also make people question the effectiveness of taTME. Third, there are more or less controversies in the selection of taTME cases, surgical procedures and cost-effectiveness. However, it can not be denied that taTME has a promising future in view of both surgical theory and clinical practice. Furthermore, taTME is a relatively safe and effective supplementary surgical procedure, especially for patients with low rectal cancer. We should attach more importance to structured training for beginners and conduct high-quality clinical studies in the future development of taTME in China, so as to ensure the safe implementation of taTME and obtain high-level evidence-based medicine evidence, and then standardize the clinical practice of taTME.

摘要

作为一种新型手术技术,经肛全直肠系膜切除术(taTME)近年来发展迅速。taTME不可避免地引发了一些关于安全性、有效性和适应证方面的质疑。首先,taTME的争议主要体现在其安全性和有效性上。一方面,手术并发症如尿道损伤、二氧化碳栓塞、吻合口漏和盆腔感染的增加,引发了对taTME安全性的担忧。其次,taTME标本质量欠佳、局部复发率增加以及taTME术后肛门功能受损,也使人们对taTME的有效性提出质疑。第三,在taTME病例选择、手术操作以及成本效益方面或多或少存在争议。然而,不可否认的是,从手术理论和临床实践来看,taTME有着广阔的前景。此外,taTME是一种相对安全有效的补充手术方式,尤其对于低位直肠癌患者。在我国taTME未来的发展中,我们应更加重视对初学者的结构化培训并开展高质量的临床研究,以确保taTME的安全实施并获得高水平的循证医学证据,进而规范taTME的临床实践。

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