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一名儿科患者中与SARS-CoV-2感染相关的脑静脉窦血栓形成:病例报告

Cerebral venous sinus thrombosis related to SARS-CoV-2 infection in a pediatric patient: A case report.

作者信息

Anh Nguyen Duong Quoc, Cuong Tran Chi, Thang Le Minh, Huy Nguyen Dao Nhat, Tran Nguyen Thi To, Giang Nguyen Luu, Tuan Ngo Minh, Bich Bui Thi, Tung Vo Thanh, Duc Nguyen Minh

机构信息

Department of Radiology, Can Tho S.I.S General Hospital, Can Tho, Vietnam.

Digital Subtraction Angiography Unit, Can Tho S.I.S General Hospital, Can Tho, Vietnam.

出版信息

Radiol Case Rep. 2023 Aug 2;18(10):3592-3597. doi: 10.1016/j.radcr.2023.07.060. eCollection 2023 Oct.

Abstract

Coronavirus disease 2019 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); it has recently been associated with several hematologic disorders. A 4-year-old boy who had SARS-CoV-2 10 months prior was admitted to the emergency department of our hospital with seizures. His SARS-CoV-2 IgG II level was 885.7 AU/mL. Neuroimaging with cranial computed tomography after admission showed abnormal images of the venous sinus, but this was not sufficient to diagnose cerebral venous sinus thrombosis. Therefore, magnetic resonance imaging and digital subtraction angiography were conducted, which confirmed the diagnosis. He was treated with thrombectomy and anticoagulation drugs, and the clinical outcomes were satisfactory. Because our patient had a medical history of SARS-CoV-2 and exhibited no other risk factors, we present this case as evidence of a potential association between cerebral venous sinus thrombosis and SARS-CoV-2.

摘要

2019冠状病毒病是由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的一种传染病;最近它与几种血液系统疾病有关。一名10个月前感染SARS-CoV-2的4岁男孩因癫痫发作被送往我院急诊科。他的SARS-CoV-2 IgG II水平为885.7 AU/mL。入院后进行的头颅计算机断层扫描神经影像学检查显示静脉窦图像异常,但这不足以诊断脑静脉窦血栓形成。因此,进行了磁共振成像和数字减影血管造影,确诊了该病。他接受了血栓切除术和抗凝药物治疗,临床结果令人满意。由于我们的患者有SARS-CoV-2病史且无其他危险因素,我们将此病例作为脑静脉窦血栓形成与SARS-CoV-2之间潜在关联的证据予以呈现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7e0/10415814/338989012aeb/gr1.jpg

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