From the Department of Sociology, University of Central Florida, Orlando, FL (JAF); Center for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, MI (JAF, SEMC, TSS); Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI (SEMC); Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI (SEMC); Institute for Social Research, University of Michigan, Ann Arbor, MI (SEMC); Department of Psychology, Texas State University, San Marcos, TX (TSS).
J Addict Med. 2023;17(4):379-386. doi: 10.1097/ADM.0000000000001131. Epub 2023 Jan 19.
While alcohol use and prescription drug misuse (PDM) are common among adolescents, there is relatively little research on coingestion. This is disquieting as polysubstance use has become a major contributing factor in drug overdose deaths among young people in the United States.
The current research uses multiple years of data from the National Survey on Drug Use and Health (2015-2019) to assess characteristics associated with coingestion among adolescents aged 12 to 17 years ( N = 57,352). Multinomial logistic regression analysis is used to identify characteristics associated with past 30-day PDM with and without alcohol coingestion. The primary objective is to determine how youth experiences with parents, involvement in conventional activities, religiosity, social support, and school status are associated with coingestion.
Among adolescents who report past 30-day PDM, 18.6% coingest with alcohol and 77.5% of adolescents who coingest report at least one substance use disorder. Several youth experiences were significantly associated with opioid coingestion including increased conflict with parents (relative risk ratio [RRR], 1.27; 95% confidence interval [CI], 1.07-1.48), lower levels of religiosity (RRR, 0.72; 95% CI, 0.52-0.98), less social support (RRR, 0.36; 95% CI, 0.18-0.69), and not being in school (RRR, 3.86; 95% CI, 1.33-11.17). In addition, emergency department visits, depression, and other substance use behaviors were also significantly associated with coingestion.
Findings demonstrate a strong connection between coingestion and substance use disorder among US adolescents. The findings from the current study can inform prevention and intervention efforts by identifying youth experiences and health-related factors that are associated with coingestion.
尽管青少年中普遍存在饮酒和处方药物滥用（PDM）的现象，但对于共摄入的研究相对较少。这令人不安，因为在美国，年轻人药物过量死亡的主要因素之一就是多物质使用。
本研究使用了国家药物使用与健康调查（2015-2019 年）的多年数据，评估了与 12 至 17 岁青少年共摄入相关的特征（N=57352）。采用多项逻辑回归分析确定了过去 30 天内 PDM 与是否与酒精共摄入相关的特征。主要目的是确定青少年与父母的相处经历、参与常规活动、宗教信仰、社会支持和学校状况与共摄入的关系。
在报告过去 30 天内 PDM 的青少年中，18.6%与酒精共摄入，77.5%与酒精共摄入的青少年报告至少有一种物质使用障碍。一些青少年的经历与阿片类药物共摄入显著相关，包括与父母的冲突增加（相对风险比 [RRR]，1.27；95%置信区间 [CI]，1.07-1.48）、宗教信仰程度降低（RRR，0.72；95% CI，0.52-0.98）、社会支持较少（RRR，0.36；95% CI，0.18-0.69）和未上学（RRR，3.86；95% CI，1.33-11.17）。此外，急诊就诊、抑郁和其他物质使用行为也与共摄入显著相关。
研究结果表明，美国青少年共摄入与物质使用障碍之间存在密切联系。本研究的结果可以通过识别与共摄入相关的青少年经历和健康相关因素，为预防和干预工作提供信息。
