Department of Cardiovascular Sciences, East Carolina University Health Medical Center and Brody School of Medicine, Greenville, NC, United States.
Center for Clinical Investigation, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Nutr Metab Cardiovasc Dis. 2023 Dec;33(12):2413-2418. doi: 10.1016/j.numecd.2023.07.027. Epub 2023 Jul 25.
While the association of potato consumption with risk factors for coronary artery disease has been inconsistent, no data are available in the literature on the influence of potato consumption on subclinical disease. Thus, we sought to examine whether baked/mashed potato consumption is associated with calcified atherosclerotic plaques in the coronary arteries.
In a cross-sectional design, we studied 2208 participants of the NHLBI Family Heart Study. These subjects were selected based on their elevated cardiovascular disease risk compared to the general population. Potato consumption was assessed by a semi-quantitative food frequency questionnaire. We defined prevalent CAC using an Agatston score of at least 100 and fitted generalized estimating equations to calculate prevalence odds ratios of CAC. Mean age at initial clinic visit was 58.2 years and 55% were female. Median consumption of potatoes was 2-4/week. There was no statistically significant association between frequency of potato consumption and prevalent CAC: odds ratios (95% CI) for CAC were 1.0 (reference), 0.85 (0.56-1.30), 0.85 (0.58-1.26), and 0.95 (0.60-1.53) among subjects reporting potato consumption of <1/week, 1/week, 2-4/week, and 5+/week, respectively (p for linear trend 0.83), adjusting for age, sex, BMI, smoking, exercise, diabetes, hypertension, total calories, prevalent coronary heart disease, income, education, and daily red meat intake.
We found no significant association between baked/mashed potato consumption and CAC in older adults.
NCT00005136. Study registration date: 5/25/2000.
尽管食用土豆与冠心病危险因素之间的关联并不一致，但目前文献中尚无关于食用土豆对亚临床疾病影响的相关数据。因此，我们试图研究烤/土豆泥的食用是否与冠状动脉中的钙化粥样硬化斑块有关。
在一项横断面设计中，我们研究了 NHLBI 家庭心脏研究的 2208 名参与者。这些对象是根据与普通人群相比心血管疾病风险较高而选择的。通过半定量食物频率问卷评估土豆的摄入量。我们使用至少 100 分的 Agatston 评分定义 CAC 的患病率，并使用广义估计方程计算 CAC 的患病率比值比。初次就诊时的平均年龄为 58.2 岁，55%为女性。土豆的中位数摄入量为每周 2-4 次。土豆食用频率与 CAC 的患病率之间没有统计学上的显著关联：每周摄入<1 次、1 次、2-4 次和 5 次或更多次的 CAC 患病率比值比（95%置信区间）分别为 1.0（参考）、0.85（0.56-1.30）、0.85（0.58-1.26）和 0.95（0.60-1.53）（p 趋势检验值为 0.83），调整了年龄、性别、BMI、吸烟、运动、糖尿病、高血压、总热量、冠心病的患病率、收入、教育程度和每日红肉摄入量。
我们发现烤/土豆泥的食用与老年人的 CAC 之间没有显著关联。
NCT00005136。研究注册日期：2000 年 5 月 25 日。
