Larsson Susanna C, Wolk Alicja
Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Am J Clin Nutr. 2016 Nov;104(5):1245-1252. doi: 10.3945/ajcn.116.142422. Epub 2016 Sep 28.
Whether consumption of potatoes, which are rich in potassium and have a high glycemic index and glycemic load, is associated with the risk of cardiovascular disease (CVD) is unknown.
The aim was to examine the association between potato consumption and risk of total and specific CVD events as well as mortality from CVD in 2 prospective cohorts of Swedish adults, a population with a high consumption of potatoes.
Information on potato consumption was available from 69,313 men and women, free of CVD and diabetes, in the Cohort of Swedish Men and the Swedish Mammography Cohort. Nonfatal and fatal cases of CVD diagnosed over 13 y of follow-up were identified by linkage with the Swedish National Patient and Cause of Death Registers. Analyses were conducted by using a Cox proportional hazards regression model, controlled for potential confounders.
We ascertained 10,147 major CVD events [myocardial infarction (MI), heart failure (HF), and stroke] and 4003 deaths due to CVD. Total potato consumption was not associated with the risk of major CVD events, specific CVD endpoints, or CVD mortality in either men or women. Multivariable HRs (95% CIs) per an increment of 3 servings/wk of total potato consumption (boiled potatoes, fried potatoes, and French fries) were 1.00 (0.97, 1.02) for major CVD events, 1.01 (0.97, 1.04) for MI, 0.97 (0.93, 1.02) for HF, 1.01 (0.97, 1.05) for stroke, and 0.99 (0.95, 1.03) for CVD mortality. There were no significant trends between the consumption of boiled potatoes, fried potatoes, or French fries and risk of any CVD outcome.
Potato consumption was not associated with the risk of CVD in this population. The Swedish Mammography Cohort and the Cohort of Swedish Men are registered at clinicaltrials.gov as NCT01127698 and NCT01127711, respectively.
富含钾且血糖生成指数和血糖负荷较高的土豆的食用与心血管疾病（CVD）风险之间的关系尚不清楚。
旨在研究瑞典成年人的2个前瞻性队列（土豆消费量较高的人群）中土豆食用量与总心血管疾病事件及特定心血管疾病事件风险以及心血管疾病死亡率之间的关联。
从瑞典男性队列和瑞典乳腺X线摄影队列中69313名无心血管疾病和糖尿病的男性和女性中获取土豆食用信息。通过与瑞典国家患者和死亡原因登记处的数据链接确定在13年随访期间诊断出的心血管疾病非致命和致命病例。使用Cox比例风险回归模型进行分析，并对潜在混杂因素进行控制。
我们确定了10147例主要心血管疾病事件[心肌梗死（MI）、心力衰竭（HF）和中风]以及4003例心血管疾病死亡病例。无论是男性还是女性，土豆总食用量均与主要心血管疾病事件、特定心血管疾病终点或心血管疾病死亡率无关。每增加3份/周的土豆总食用量（煮土豆、炸土豆和薯条），多变量HR（95%CI）对于主要心血管疾病事件为1.00（0.97，1.02），对于心肌梗死为1.01（0.97，1.04），对于心力衰竭为0.97（0.93，1.02），对于中风为1.01（0.97，1.05），对于心血管疾病死亡率为0.99（0.95，1.03）。煮土豆、炸土豆或薯条的食用量与任何心血管疾病结局风险之间均无显著趋势。
在该人群中，土豆食用量与心血管疾病风险无关。瑞典乳腺X线摄影队列和瑞典男性队列在clinicaltrials.gov上的注册编号分别为NCT01127698和NCT01127711。
