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Abatacept for graft versus host disease prophylaxis in patients 60 years and older receiving mismatched unrelated donor transplantation for hematologic malignancies.

作者信息

Raghunandan Sharmila, Qayed Muna, Watkins Ben K, Graiser Michael, Gorfinkel Lev, Westbrook Adrianna, Gillespie Scott, Bratrude Brandi, Petrovic Aleksandra, Suessmuth Yvonne, Horan John, Kean Leslie S, Langston Amelia A

机构信息

Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, USA.

Emory University, Atlanta, GA, USA.

出版信息

Bone Marrow Transplant. 2023 Nov;58(11):1264-1266. doi: 10.1038/s41409-023-02043-y. Epub 2023 Aug 14.

DOI:10.1038/s41409-023-02043-y
PMID:37580397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10622309/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1dc/10622309/2e23a1112bfc/41409_2023_2043_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1dc/10622309/2e23a1112bfc/41409_2023_2043_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1dc/10622309/2e23a1112bfc/41409_2023_2043_Fig1_HTML.jpg

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Abatacept for graft versus host disease prophylaxis in patients 60 years and older receiving mismatched unrelated donor transplantation for hematologic malignancies.阿巴西普用于预防60岁及以上接受错配无关供体移植治疗血液系统恶性肿瘤患者的移植物抗宿主病。
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本文引用的文献

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Allogeneic hematopoietic cell transplantation for older patients.异基因造血细胞移植治疗老年患者。
Hematology Am Soc Hematol Educ Program. 2021 Dec 10;2021(1):254-263. doi: 10.1182/hematology.2021000257.
2
How old is too old for a transplant?对于移植来说,年龄多大算太大了?
Best Pract Res Clin Haematol. 2021 Mar;34(1):101243. doi: 10.1016/j.beha.2021.101243. Epub 2021 Jan 12.
3
Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD.阿巴西普阻断共刺激用于预防急性移植物抗宿主病的 II 期临床试验。
Blood. 2025 Jun 12;145(24):2847-2856. doi: 10.1182/blood.2024024247.
J Clin Oncol. 2021 Jun 10;39(17):1865-1877. doi: 10.1200/JCO.20.01086. Epub 2021 Jan 15.
4
Risk factors for acute GVHD and survival after hematopoietic cell transplantation.造血细胞移植后急性移植物抗宿主病的危险因素和生存情况。
Blood. 2012 Jan 5;119(1):296-307. doi: 10.1182/blood-2011-06-364265. Epub 2011 Oct 18.
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HLA-C antigen mismatch is associated with worse outcome in unrelated donor peripheral blood stem cell transplantation.HLA-C 抗原错配与无关供体外周血造血干细胞移植后不良结局相关。
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Abatacept.阿巴西普
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