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机器人辅助与传统腹腔镜手术治疗中低位直肠癌的比较:系统评价和荟萃分析。

Comparison of robotic‑assisted versus conventional laparoscopic surgery for mid-low rectal cancer: a systematic review and meta-analysis.

机构信息

Northern Jiangsu People's Hospital Affiliated to Dalian Medical University, Yangzhou, 225001, China.

General Surgery Institute of Yangzhou, Yangzhou University, Yangzhou, 225001, China.

出版信息

J Cancer Res Clin Oncol. 2023 Nov;149(16):15207-15217. doi: 10.1007/s00432-023-05228-6. Epub 2023 Aug 14.

Abstract

PURPOSE

Scarce research has reported the comparison between robotic and laparoscopic surgery in mid-low rectal cancer. Therefore, this meta-analysis is aimed to compare the safety and efficacy of the two surgical approaches.

METHODS

A comprehensive search of the databases (PubMed, EMBASE, Cochrane, and Web of Science) was performed for studies comparing robotic and laparoscopic surgery. The outcomes of interest acquired from eight articles included three aspects: intraoperative conditions, postoperative status of patients, and complications. All data (robotic = 1350 patients, laparoscopic = 1330 patients) enrolled were analyzed using Rev Man 5.4.

RESULTS

Compared to the laparoscopic group, the robotic group indicated a noticeable superiority in estimated blood loss (P < 0.0001), number of lymph nodes dissected (P = 0.004), time to first flatus (P = 0.001), time to first fluid diet (P = 0.001), hospital stay (P < 0.0001), conversion (P = 0.009), and urinary retention (P = 0.0006), but devoted much more operation time (P = 0.0004).

CONCLUSION

Robotic surgery was associated with superiority over laparoscopic surgery in increasing surgical safety, accelerating postoperative recovery, and reducing complications, which suggested that robotic surgery could be a safe and effective method for treating mid-low rectal cancer.

摘要

目的

鲜有研究报道机器人手术与腹腔镜手术治疗中低位直肠癌的比较。因此,本荟萃分析旨在比较两种手术方法的安全性和疗效。

方法

对PubMed、EMBASE、Cochrane 和 Web of Science 数据库进行全面检索,以比较机器人手术和腹腔镜手术的研究。从 8 篇文章中获取了 3 个方面的感兴趣结局:术中情况、患者术后状况和并发症。使用 Rev Man 5.4 分析所有纳入的数据(机器人组=1350 例,腹腔镜组=1330 例)。

结果

与腹腔镜组相比,机器人组的术中估计出血量(P<0.0001)、淋巴结清扫数量(P=0.004)、首次排气时间(P=0.001)、首次流质饮食时间(P=0.001)、住院时间(P<0.0001)、中转率(P=0.009)和尿潴留发生率(P=0.0006)明显更优,但手术时间更长(P=0.0004)。

结论

机器人手术在提高手术安全性、加速术后恢复和减少并发症方面优于腹腔镜手术,提示机器人手术可能是治疗中低位直肠癌的一种安全有效的方法。

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