Department of Plastic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing.
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
J Craniofac Surg. 2023 Oct 1;34(7):e708-e710. doi: 10.1097/SCS.0000000000009614. Epub 2023 Aug 15.
Patients with localized scleroderma (LS) often have to seek plastic surgery to improve facial esthetic impairment.
The authors reported a case of the reactivation of LS after autologous fat grafting (AFG).
A man presented with facial atrophy and skin fibrosis on the cheek with a history of LS. The disease had remained stable for 9 years and he was suggested to stop oral medication. With irreversible esthetic impairment on the face, he sought plastic surgery for improvement. He underwent twice AFG into the right cheek with about 60 mL fat graft each. The donor sites were the abdomen and both thighs.
Six months after the last AFG, the patient found new lesions occur on the lateral forehead. The patient was later diagnosed with reactivation of LS.
The understanding of the surgical risk and perioperative management for patients with LS needs more research.
局限性硬皮病（LS）患者常需要寻求整形手术来改善面部美观受损。
作者报告了一例自体脂肪移植（AFG）后 LS 再激活的病例。
一名男性因面颊部萎缩和皮肤纤维化就诊，有 LS 病史。该病已稳定 9 年，建议停止口服药物治疗。由于面部美观受损不可逆转，他寻求整形手术改善。他接受了两次右侧面颊 AFG，每次约 60 毫升脂肪移植。供区为腹部和双侧大腿。
最后一次 AFG 后 6 个月，患者发现额外侧出现新的皮损。患者后来被诊断为 LS 再激活。
对于 LS 患者，需要更多的研究来了解手术风险和围手术期管理。
