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[化脓性伤口微生物群落结构及其对抗生素的敏感性]

[Structure of the microflora of suppurative wounds and its sensitivity to antibiotics].

作者信息

Grigorian A V, Gamaleia L A, Tolstykh P I, Struchkov Iu V, Sazhin V P

出版信息

Antibiotiki. 1979 Apr;24(4):306-12.

PMID:375824
Abstract

Clinico-bacteriological examination of patients with purulent infections showed that Staphylococcus was the predominating microflora in the wounds. Simultaneously an increasing role of gram-negative conditionally pathogenic bacteria was shown. Multiple drug resistance was found in the organisms tested. The highest sensitivity levels were observed to gentamicin, kanamycin, tetracycline, levomycetin. It was shown by means of special typing methods that staphylococci of phage group III and Ps. Aeruginosa of serotype II predominated in the infected wounds. When the pathological material contained the antibiotic resistant cultures of Ps. aeruginosa, Proteus, Klebsiella and toxigenic strains of Staphylococcus, a tendency for prolongation of the suppurative process was observed.

摘要

对化脓性感染患者进行的临床细菌学检查表明,葡萄球菌是伤口中的主要菌群。同时,革兰氏阴性条件致病菌的作用也日益显现。在所检测的菌株中发现了多重耐药性。观察到对庆大霉素、卡那霉素、四环素、氯霉素的敏感性最高。通过特殊的分型方法表明,III型噬菌体葡萄球菌和II型血清型铜绿假单胞菌在感染伤口中占主导地位。当病理材料中含有铜绿假单胞菌、变形杆菌、克雷伯菌的耐抗生素培养物以及葡萄球菌的产毒菌株时,观察到化脓过程有延长的趋势。

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