通过膜微粘度变化对线粒体中3-磷酸甘油氧化的调节。
Regulation of glycerol 3-phosphate oxidation in mitochondria by changes in membrane microviscosity.
作者信息
Amler E, Rauchová H, Svobodová J, Drahota Z
出版信息
FEBS Lett. 1986 Sep 29;206(1):1-3. doi: 10.1016/0014-5793(86)81328-x.
PMID:3758342
Abstract
The inhibition of glycerol 3-phosphate oxidation by oleic acid correlates with changes in membrane microviscosity monitored by the steady-state fluorescence anisotropy of DPH. The dynamic measurements indicate that the changes of both the limiting anisotropy and rotational relaxation time occur in a concentration range where the enzyme activity is strongly inhibited.
摘要
油酸对3-磷酸甘油氧化的抑制作用与通过DPH稳态荧光各向异性监测的膜微粘度变化相关。动态测量表明，在酶活性受到强烈抑制的浓度范围内，极限各向异性和旋转弛豫时间均发生变化。
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