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人类乳腺癌中的雌激素受体浓度与巨噬细胞浸润

Oestrogen receptor concentration and macrophage infiltration in human breast cancer.

作者信息

Steele R J, Eremin O, Brown M, Hawkins R A

出版信息

Eur J Surg Oncol. 1986 Sep;12(3):273-6.

PMID:3758366
Abstract

Oestrogen receptor concentration and percentage macrophage content were estimated in 40 human primary breast cancers. Macrophages were identified by Fc (IgG) receptor expression and by the presence of a macrophage-associated antigen. A significant inverse correlation between receptor concentration and macrophage content was found, and this was strengthened by correcting receptor level for tumour cellularity.

摘要

对40例原发性人类乳腺癌进行了雌激素受体浓度和巨噬细胞含量百分比的评估。通过Fc(IgG)受体表达以及巨噬细胞相关抗原的存在来识别巨噬细胞。发现受体浓度与巨噬细胞含量之间存在显著的负相关,并且通过校正肿瘤细胞密度的受体水平,这种相关性得到了加强。

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