Kurada Bapi Raju V, Umeh Chukwuemeka A, Gupta Rakesh C, Onyi Stella C, Penaherrera Jose
Internal Medicine, Hemet Global Medical Center, Hemet, USA.
Medicine, St. George's University School of Medicine, Grenada, GRD.
Cureus. 2023 Jul 15;15(7):e41928. doi: 10.7759/cureus.41928. eCollection 2023 Jul.
Behcet's disease (BD) is a chronic systemic inflammatory vasculitis with a relapsing and remitting course. The disease predominantly affects males between the ages of 20 and 40 years. The disease is more prevalent in Middle Eastern and Asian countries but is less common in North American countries. BD typically presents as recurrent oro-genital ulcers and ocular inflammation. Pulmonary vasculitis with pulmonary arterial involvement is a unique manifestation, with most pulmonary manifestations occurring later in the disease course. Here, we report a case with pulmonary arterial aneurysms and variable arterial-venous thrombosis in a young African American Male diagnosed with BD after he presented with pulmonary manifestations. This report emphasizes that a high index of suspicion is needed to diagnose a rare condition with such variable manifestations as Behcet's disease and that early detection and immunosuppression therapy can confer improved prognosis.
白塞病（BD）是一种慢性全身性炎症性血管炎，病程呈复发缓解型。该疾病主要影响20至40岁的男性。在中东和亚洲国家更为普遍，但在北美国家较少见。BD通常表现为复发性口腔和生殖器溃疡以及眼部炎症。累及肺动脉的肺部血管炎是一种独特的表现，大多数肺部表现出现在疾病病程后期。在此，我们报告一例年轻非裔美国男性病例，该患者出现肺部表现后被诊断为BD，伴有肺动脉瘤和多变的动静脉血栓形成。本报告强调，对于诊断像白塞病这样具有如此多变表现的罕见疾病需要高度怀疑指数，并且早期检测和免疫抑制治疗可改善预后。
