• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Why caution should be applied when interpreting and promoting findings from Mendelian randomisation studies.

作者信息

Carter Alice R, Fraser Abigail, Howe Laura D, Harris Sian, Hughes Amanda

机构信息

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

Population Health Sciences, University of Bristol, Bristol, UK.

出版信息

Gen Psychiatr. 2023 Aug 10;36(4):e101047. doi: 10.1136/gpsych-2023-101047. eCollection 2023.

DOI:10.1136/gpsych-2023-101047
PMID:37583791
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10423826/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1846/10423826/de56fc7e82ec/gpsych-2023-101047f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1846/10423826/de56fc7e82ec/gpsych-2023-101047f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1846/10423826/de56fc7e82ec/gpsych-2023-101047f02.jpg

相似文献

1
Why caution should be applied when interpreting and promoting findings from Mendelian randomisation studies.在解释和推广孟德尔随机化研究结果时为何应谨慎。
Gen Psychiatr. 2023 Aug 10;36(4):e101047. doi: 10.1136/gpsych-2023-101047. eCollection 2023.
2
Mendelian randomisation for nutritional psychiatry.营养精神病学的孟德尔随机化研究
Lancet Psychiatry. 2020 Feb;7(2):208-216. doi: 10.1016/S2215-0366(19)30293-7. Epub 2019 Nov 20.
3
[Mendelian randomisation - a genetic approach to an epidemiological method].[孟德尔随机化——一种流行病学方法的遗传学途径]
Tidsskr Nor Laegeforen. 2016 Jun 21;136(11):1002-5. doi: 10.4045/tidsskr.15.1262. eCollection 2016 Jun.
4
Mendelian randomisation for psychiatry: how does it work, and what can it tell us?精神医学中的孟德尔随机化：它是如何运作的，又能告诉我们什么？
Mol Psychiatry. 2022 Jan;27(1):53-57. doi: 10.1038/s41380-021-01173-3. Epub 2021 Jun 4.
5
Mendelian randomisation studies for causal inference in chronic obstructive pulmonary disease: A narrative review.用于慢性阻塞性肺疾病因果推断的孟德尔随机化研究：一项叙述性综述。
Pulmonology. 2025 Dec 31;31(1):2470556. doi: 10.1080/25310429.2025.2470556. Epub 2025 Feb 25.
6
Distinct pathway-based effects of blood pressure and body mass index on cardiovascular traits: comparison of novel Mendelian randomization approaches.血压和体重指数对心血管特征的基于不同通路的影响：新型孟德尔随机化方法的比较
Genome Med. 2025 May 15;17(1):54. doi: 10.1186/s13073-025-01472-2.
7
Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.血浆尿酸浓度与冠心病风险：孟德尔随机分析。
Lancet Diabetes Endocrinol. 2016 Apr;4(4):327-36. doi: 10.1016/S2213-8587(15)00386-1. Epub 2016 Jan 16.
8
Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies.血清钙水平升高的健康影响：更新的全表型孟德尔随机化研究和孟德尔随机化研究综述。
EBioMedicine. 2022 Feb;76:103865. doi: 10.1016/j.ebiom.2022.103865. Epub 2022 Feb 6.
9
Childhood adiposity and novel subtypes of diabetes in adults: a Mendelian randomisation and genome-wide genetic correlation study.儿童肥胖与成人新型糖尿病亚型：一项孟德尔随机化和全基因组遗传相关性研究。
Lancet Glob Health. 2023 Mar;11 Suppl 1:S1. doi: 10.1016/S2214-109X(23)00086-4.
10
Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies.血清尿酸水平与多种健康结局：观察性研究、随机对照试验及孟德尔随机化研究证据的综合评价
BMJ. 2017 Jun 7;357:j2376. doi: 10.1136/bmj.j2376.

引用本文的文献

1
Unveiling causal relationship between white matter tracts and psychiatric disorders.揭示白质束与精神疾病之间的因果关系。
Commun Biol. 2025 Aug 14;8(1):1221. doi: 10.1038/s42003-025-08669-6.
2
Genetically Elevated Selenoprotein S Levels and Risk of Stroke: A Two-Sample Mendelian Randomization Analysis.遗传升高的硒蛋白S水平与中风风险：一项两样本孟德尔随机化分析。
Int J Mol Sci. 2025 Feb 14;26(4):1652. doi: 10.3390/ijms26041652.
3
Causal relationship between hyperthyroidism and cataracts: a two-sample bi-directional mendelian randomization study.

本文引用的文献

1
Mendelian randomization.孟德尔随机化
Nat Rev Methods Primers. 2022 Feb 10;2. doi: 10.1038/s43586-021-00092-5.
2
Bias correction for inverse variance weighting Mendelian randomization.基于逆方差加权的孟德尔随机化偏倚校正。
Genet Epidemiol. 2023 Jun;47(4):314-331. doi: 10.1002/gepi.22522. Epub 2023 Apr 10.
3
Investigating genetic causal relationships between blood pressure and anxiety, depressive symptoms, neuroticism and subjective well-being.研究血压与焦虑、抑郁症状、神经质和主观幸福感之间的遗传因果关系。
甲状腺功能亢进症与白内障之间的因果关系：两样本双向孟德尔随机化研究。
Sci Rep. 2024 Oct 23;14(1):24972. doi: 10.1038/s41598-024-76151-0.
4
Psychiatric comorbidities in epilepsy: population co-occurrence, genetic correlations and causal effects.癫痫中的精神科共病：人群共现、遗传相关性及因果效应。
Gen Psychiatr. 2024 Jan 30;37(1):e101201. doi: 10.1136/gpsych-2023-101201. eCollection 2024.
5
Causal relationship between genetically determined plasma metabolites and skin cancer: a two-sample Mendelian randomization study.遗传决定的血浆代谢物与皮肤癌之间的因果关系：两样本孟德尔随机化研究。
Arch Dermatol Res. 2024 May 24;316(6):214. doi: 10.1007/s00403-024-03011-2.
6
Inaccurate measures of outcomes in the two-sample Mendelian randomization of vitamin D with miscarriage.维生素D与流产的两样本孟德尔随机化中结局测量的不准确情况。
Hum Reprod Open. 2024 Apr 27;2024(2):hoae025. doi: 10.1093/hropen/hoae025. eCollection 2024.
7
Causal inference between pernicious anemia and cancers: a bidirectional two-sample mendelian randomization analysis.两样本孟德尔随机化分析探讨恶性贫血与癌症之间的因果关系。
BMC Cancer. 2024 May 13;24(1):586. doi: 10.1186/s12885-024-12354-y.
8
The causal relationship between genetically predicted blood metabolites and idiopathic pulmonary fibrosis: A bidirectional two-sample Mendelian randomization study.遗传预测血液代谢物与特发性肺纤维化之间的因果关系：双向两样本孟德尔随机化研究。
PLoS One. 2024 Apr 16;19(4):e0300423. doi: 10.1371/journal.pone.0300423. eCollection 2024.
Gen Psychiatr. 2022 Nov 4;35(5):e100877. doi: 10.1136/gpsych-2022-100877. eCollection 2022.
4
Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration.加强流行病学中基于孟德尔随机化的观察性研究报告 (STROBE-MR): 解释和详述。
BMJ. 2021 Oct 26;375:n2233. doi: 10.1136/bmj.n2233.
5
Ten simple rules for conducting a mendelian randomization study.进行孟德尔随机化研究的十条简单规则。
PLoS Comput Biol. 2021 Aug 12;17(8):e1009238. doi: 10.1371/journal.pcbi.1009238. eCollection 2021 Aug.
6
Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses.通过家系内分析避免孟德尔随机化中的家族性、选择性交配和群体分层偏倚。
Nat Commun. 2020 Jul 14;11(1):3519. doi: 10.1038/s41467-020-17117-4.
7
Population phenomena inflate genetic associations of complex social traits.人口现象夸大了复杂社会特征的遗传关联。
Sci Adv. 2020 Apr 15;6(16):eaay0328. doi: 10.1126/sciadv.aay0328. eCollection 2020 Apr.
8
Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates.孟德尔随机化分析二分类暴露变量：因果估计的解释与呈现。
Eur J Epidemiol. 2018 Oct;33(10):947-952. doi: 10.1007/s10654-018-0424-6. Epub 2018 Jul 23.
9
The MR-Base platform supports systematic causal inference across the human phenome.MR-Base 平台支持在人类表型全范围内进行系统因果推断。
Elife. 2018 May 30;7:e34408. doi: 10.7554/eLife.34408.
10
Causal associations between risk factors and common diseases inferred from GWAS summary data.从全基因组关联研究（GWAS）汇总数据推断出的风险因素与常见疾病之间的因果关联。
Nat Commun. 2018 Jan 15;9(1):224. doi: 10.1038/s41467-017-02317-2.