Deuster P A, Kyle S B, Moser P B, Vigersky R A, Singh A, Schoomaker E B
Fertil Steril. 1986 Oct;46(4):636-43.
This study was conducted to determine whether nutritional status contributes to the amenorrhea associated with long distance running. Dietary intakes and biochemical measures of nutritional status were compared in highly trained amenorrheic (AM) and eumenorrheic (EU) women runners matched for height, weight, percent fat (11% to 12%) and training distance (113 km/week). Serum estradiol (E2) (EU, 104.7 pg/ml, versus AM, 22.5 pg/ml) and cortisol (EU, 22.4 micrograms/dl, versus AM, 26.6 micrograms/dl) concentrations differed between the two groups. Three-day dietary records revealed that fat intake by AM runners was significantly lower than by EU runners (EU, 97 gm/day, versus AM, 66 gm/day). AM runners consumed large amounts of vitamin A activity, probably in the form of B-carotene, and fairly high quantities of crude fiber. Zinc intake by AM runners was well below the recommended dietary allowances (RDA), compared with EU runners (EU, 15.4 mg, versus AM, 10.9 mg). Further, plasma zinc tended to be lower for the AM runners (EU, 85.7 micrograms/dl, versus AM, 81.2 micrograms/dl). It was concluded that the potential contributions of dietary fat, B-carotene, and zinc to inducing changes in menstrual function and the metabolism of certain hormones should be investigated.
本研究旨在确定营养状况是否与长跑相关的闭经有关。对身高、体重、体脂百分比（11%至12%）和训练距离（每周113公里）相匹配的高强度训练的闭经（AM）和月经正常（EU）的女性跑步者的饮食摄入量和营养状况的生化指标进行了比较。两组之间的血清雌二醇（E2）（EU组为104.7 pg/ml，AM组为22.5 pg/ml）和皮质醇（EU组为22.4微克/分升，AM组为26.6微克/分升）浓度存在差异。三天的饮食记录显示，AM组跑步者的脂肪摄入量显著低于EU组跑步者（EU组为97克/天，AM组为66克/天）。AM组跑步者摄入了大量的维生素A活性物质，可能是以β-胡萝卜素的形式，并且摄入了相当数量的粗纤维。与EU组跑步者相比，AM组跑步者的锌摄入量远低于推荐膳食摄入量（RDA）（EU组为15.4毫克，AM组为10.9毫克）。此外，AM组跑步者的血浆锌含量往往较低（EU组为85.7微克/分升，AM组为81.2微克/分升）。得出的结论是，应研究膳食脂肪、β-胡萝卜素和锌对诱导月经功能变化和某些激素代谢的潜在作用。
