• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

丙美卡因表面麻醉联合针刺在老年白内障超声乳化术中的临床研究

Clinical study of acupuncture combined with surface anesthesia using proparacaine in geriatric cataract phacoemulsification.

作者信息

Dong Ping, Wang Li-Fang, Zhang Li-Xiang, Li Fang, Yin Hui-Su, Dou Zhi-Xia, Huang Xiu-Ju, Xu Rui, Zhang Wu-Lin

机构信息

Department of Acupuncture and Rehabilitation, Hebei Eye Hospital, Xingtai 054001, Hebei Province, China.

Department of Surgical Anesthesia, Hebei Eye Hospital, Xingtai 054001, Hebei Province, China.

出版信息

World J Clin Cases. 2023 Jul 26;11(21):5073-5082. doi: 10.12998/wjcc.v11.i21.5073.

DOI:10.12998/wjcc.v11.i21.5073
PMID:37583853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10424011/
Abstract

BACKGROUND

During anesthesia administration for cataract surgery, low pH of proparacaine may induce pain or complications such as corneal damage and poor wound healing, with the use of additional drops intraoperatively increasing the risk of complications. Accordingly, there is a clinical need for adjuncts to local anesthesia needs to improve the efficiency of anesthesia and reduce the required amount of intraoperative proparacaine.

AIM

To identify a method of anesthesia for geriatric cataract phacoemulsification that provides more efficient analgesia and improves clinical efficacy.

METHODS

A total of 130 geriatric patients with cataracts who attended Hebei Eye Hospital from December 2020 to December 2022 were included in the present study. Patients were divided into the proparacaine surface anesthesia (SA) group (65 cases) and the compound acupuncture-medicine anesthesia group (CAMA group, 65 cases). Patients in the CAMA group were provided acupuncture analgesia in addition to SA. Preoperative anxiety [Self-Rating Anxiety Scale (SAS) score and state anxiety inventory (SAI) score], intraoperative stress, vital signs, analgesia, and cooperation, as well as postoperative adverse events, were compared between groups.

RESULTS

More marked reductions in anxiety were observed among patients in the CAMA group, with corresponding reductions in SAS and SAI scores. During the operation, no change in the secretion of E, NE, or Cor group compared to the preoperative period was observed in the CAMA, which was markedly lower than that in the SA group. Heart rate, blood pressure, and respiratory rate were more stable intraoperatively in the CAMA group. In addition, the incidence of intraoperative pain and the number of additional doses of anesthesia required in the CAMA group were markedly lower than in the SA group. Accordingly, patients in the CAMA group were able to avoid eye movements and eyelid closing leading to greater cooperation with surgeons during surgery. Furthermore, marked reductions in intraoperative adverse effects were observed in the CAMA group, indicating greater overall safety.

CONCLUSION

Proparacaine SA combined with acupuncture as an analgesic provides improved analgesia with greater safety compared to surface anesthesia with proparacaine during geriatric cataract phacoemulsification.

摘要

背景

在白内障手术麻醉过程中,丙美卡因的低pH值可能会引发疼痛或诸如角膜损伤和伤口愈合不良等并发症,术中使用额外滴眼液会增加并发症风险。因此,临床上需要局部麻醉辅助手段来提高麻醉效率并减少术中丙美卡因的用量。

目的

确定一种用于老年白内障超声乳化手术的麻醉方法,该方法能提供更有效的镇痛并提高临床疗效。

方法

本研究纳入了2020年12月至2022年12月期间到河北眼科医院就诊的130例老年白内障患者。患者被分为丙美卡因表面麻醉(SA)组(65例)和复合针灸药物麻醉组(CAMA组,65例)。CAMA组患者除表面麻醉外还接受针灸镇痛。比较两组患者术前焦虑程度[自评焦虑量表(SAS)评分和状态焦虑量表(SAI)评分]、术中应激反应、生命体征、镇痛效果及配合情况,以及术后不良事件。

结果

CAMA组患者焦虑程度降低更为显著,SAS和SAI评分相应降低。手术过程中,CAMA组患者E、NE或Cor的分泌与术前相比无变化,明显低于SA组。CAMA组术中心率、血压和呼吸频率更稳定。此外,CAMA组术中疼痛发生率和所需额外麻醉剂量明显低于SA组。因此,CAMA组患者在手术过程中能够避免眼球运动和眼睑闭合,从而更配合手术医生。此外,CAMA组术中不良反应明显减少,表明总体安全性更高。

结论

在老年白内障超声乳化手术中,与丙美卡因表面麻醉相比,丙美卡因表面麻醉联合针灸作为镇痛方法可提供更好的镇痛效果且安全性更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/2684bec8f148/WJCC-11-5073-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/a49d685d531d/WJCC-11-5073-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/79f0777156ca/WJCC-11-5073-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/13186c53305c/WJCC-11-5073-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/cd84be873777/WJCC-11-5073-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/a4ddda48e56f/WJCC-11-5073-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/f374cecfe1b4/WJCC-11-5073-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/2684bec8f148/WJCC-11-5073-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/a49d685d531d/WJCC-11-5073-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/79f0777156ca/WJCC-11-5073-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/13186c53305c/WJCC-11-5073-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/cd84be873777/WJCC-11-5073-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/a4ddda48e56f/WJCC-11-5073-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/f374cecfe1b4/WJCC-11-5073-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a909/10424011/2684bec8f148/WJCC-11-5073-g007.jpg

相似文献

1
Clinical study of acupuncture combined with surface anesthesia using proparacaine in geriatric cataract phacoemulsification.丙美卡因表面麻醉联合针刺在老年白内障超声乳化术中的临床研究
World J Clin Cases. 2023 Jul 26;11(21):5073-5082. doi: 10.12998/wjcc.v11.i21.5073.
2
A single drop of 0.5% proparacaine hydrochloride for uncomplicated clear corneal phacoemulsification.用于单纯性透明角膜超声乳化术的一滴0.5%盐酸丙美卡因。
Middle East Afr J Ophthalmol. 2013 Jul-Sep;20(3):221-4. doi: 10.4103/0974-9233.114795.
3
A double-blinded randomized clinical trial for pain perception: The efficacy and safety of topical cold saline solution anesthesia in phacoemulsification.一项关于疼痛感知的双盲随机临床试验:局部冷盐水溶液麻醉在超声乳化术中的疗效和安全性。
Indian J Ophthalmol. 2022 Jan;70(1):124-130. doi: 10.4103/ijo.IJO_876_21.
4
Manual small-incision cataract surgery under topical anesthesia.局部麻醉下的手法小切口白内障手术。
Indian J Ophthalmol. 2022 Nov;70(11):4026-4028. doi: 10.4103/ijo.IJO_1742_22.
5
Oral acetaminophen (paracetamol) for additional analgesia in phacoemulsification cataract surgery performed using topical anesthesia Randomized double-masked placebo-controlled trial.局部麻醉下超声乳化白内障手术中口服对乙酰氨基酚(扑热息痛)作为额外镇痛剂的随机双盲安慰剂对照试验。
J Cataract Refract Surg. 2010 Mar;36(3):402-6. doi: 10.1016/j.jcrs.2009.09.035.
6
Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract surgery in adults.局部麻醉联合前房内注射利多卡因与单纯局部麻醉用于成人白内障超声乳化手术的比较
Cochrane Database Syst Rev. 2020 Jul 28;7(7):CD005276. doi: 10.1002/14651858.CD005276.pub4.
7
Monitored anesthesia care provided by registered respiratory care practitioners during cataract surgery: a report of 1957 cases.注册呼吸治疗师在白内障手术期间提供的监护麻醉护理:1957例报告。
Ophthalmology. 2005 Feb;112(2):272-7. doi: 10.1016/j.ophtha.2004.08.016.
8
Comparison of surgeon comfort assessment during phacoemulsification using bilateral topical anesthesia versus ipsilateral topical anesthesia: a randomized controlled study.双侧表面麻醉与同侧表面麻醉在白内障超声乳化术中外科医生舒适度评估的比较:一项随机对照研究。
Int Ophthalmol. 2018 Jun;38(3):1235-1242. doi: 10.1007/s10792-017-0587-2. Epub 2017 Jun 14.
9
Combined acupuncture-medicine anesthesia used in thyroid surgery: A systematic review and meta-analysis.针刺-药物联合麻醉在甲状腺手术中的应用:系统评价和荟萃分析。
Medicine (Baltimore). 2023 Jan 6;102(1):e32582. doi: 10.1097/MD.0000000000032582.
10
An Analysis of the Use of Proparacaine in Cataract Surgery.丙美卡因在白内障手术中的应用分析
Cureus. 2022 Feb 13;14(2):e22175. doi: 10.7759/cureus.22175. eCollection 2022 Feb.

引用本文的文献

1
Based on the relationship between anxiety of existential meaninglessness, hope level, and fear of progression, explored the effect of preoperative nursing with Orem theory in the senile cataract population.基于存在意义焦虑、希望水平与病情进展恐惧之间的关系,探讨奥瑞姆理论术前护理在老年白内障人群中的效果。
Front Psychol. 2024 May 10;15:1358229. doi: 10.3389/fpsyg.2024.1358229. eCollection 2024.

本文引用的文献

1
[Femtolaser-assisted phacoemulsification of intumescent cataract].[飞秒激光辅助膨胀期白内障超声乳化术]
Vestn Oftalmol. 2022;138(1):13-22. doi: 10.17116/oftalma202213801113.
2
Effect of Acupuncture Stimulation of Hegu (LI4) and Taichong (LR3) on the Resting-State Networks in Alzheimer's Disease: Beyond the Default Mode Network.针刺合谷(LI4)和太冲(LR3)对阿尔茨海默病静息态网络的影响:超越默认模式网络。
Neural Plast. 2021 Mar 8;2021:8876873. doi: 10.1155/2021/8876873. eCollection 2021.
3
Identification, synthesis and structural confirmation of process-related impurities in proparacaine hydrochloride.
盐酸丙美卡因有关物质的鉴定、合成与结构确证。
J Pharm Biomed Anal. 2020 Oct 25;190:113497. doi: 10.1016/j.jpba.2020.113497. Epub 2020 Jul 29.
4
Retinal detachment following cataract phacoemulsification-a review of the literature.白内障超声乳化术后视网膜脱离——文献复习。
Eye (Lond). 2020 Apr;34(4):616-631. doi: 10.1038/s41433-019-0575-z. Epub 2019 Oct 1.
5
Cataract, phacoemulsification and intraocular pressure: Is the anterior segment anatomy the missing piece of the puzzle?白内障、超声乳化术和眼内压:前节解剖结构是否是未解之谜的缺失部分?
Prog Retin Eye Res. 2018 May;64:77-83. doi: 10.1016/j.preteyeres.2018.01.003. Epub 2018 Jan 31.
6
Optimal Dose of Dexmedetomidine Retrobulbar Anesthesia during Phacoemulsification Cataract Surgery.白内障超声乳化手术中球后麻醉右美托咪定的最佳剂量
Anesth Essays Res. 2017 Oct-Dec;11(4):1046-1050. doi: 10.4103/aer.AER_116_17.
7
Acupuncture Decreases Blood Pressure Related to Hypothalamus Functional Connectivity with Frontal Lobe, Cerebellum, and Insula: A Study of Instantaneous and Short-Term Acupuncture Treatment in Essential Hypertension.针刺通过降低下丘脑与额叶、小脑及脑岛的功能连接来降低血压:一项关于原发性高血压即时和短期针刺治疗的研究
Evid Based Complement Alternat Med. 2016;2016:6908710. doi: 10.1155/2016/6908710. Epub 2016 Sep 4.
8
Laser-assisted cataract surgery versus standard ultrasound phacoemulsification cataract surgery.激光辅助白内障手术与标准超声乳化白内障手术对比
Cochrane Database Syst Rev. 2016 Jul 8;7(7):CD010735. doi: 10.1002/14651858.CD010735.pub2.
9
[Effects of Acupuncture Stimulation of Bilateral "Hegu" (LI 4) and "Taichong" (LR 3) on Learning-memory Ability, Hippocampal AP 42 Expression and Inflammatory Cytokines in Rats with Alzheimer's Disease].针刺双侧“合谷”(LI 4)和“太冲”(LR 3)对阿尔茨海默病大鼠学习记忆能力、海马AP 42表达及炎性细胞因子的影响
Zhen Ci Yan Jiu. 2016 Apr;41(2):113-8.
10
Degree of corneal anaesthesia after topical application of 0.4% oxybuprocaine hydrochloride and 0.5% proparacaine hydrochloride ophthalmic solution in clinically normal cattle.在临床正常牛中局部应用0.4%盐酸奥布卡因和0.5%丙美卡因滴眼液后的角膜麻醉程度。
Aust Vet J. 2016 Jun;94(6):181-5. doi: 10.1111/avj.12443.