Koret Vision Center, Department of Ophthalmology, University of California, San Francisco Medical School, 10 Koret Way, San Francisco, CA 94143, United States.
Koret Vision Center, Department of Ophthalmology, University of California, San Francisco Medical School, 10 Koret Way, San Francisco, CA 94143, United States.
Prog Retin Eye Res. 2018 May;64:77-83. doi: 10.1016/j.preteyeres.2018.01.003. Epub 2018 Jan 31.
Cataract extraction is a safe and effective surgery that has a lowering effect on the intraocular pressure. The specific mechanisms for this effect are still unclear. A direct inflammatory effect on the trabecular meshwork, alteration of the blood aqueous barrier, changes in the ciliary body and mechanical changes of the anterior segment anatomy are the key to understand cataract surgery and it's effects on aqueous humor dynamics. Additionally, with the advent of AS OCT, changes in the anterior segment of the eye have been studied and several parameters (such as lens vault, angle opening distance and anterior chamber depth) have been identified as predictors of intraocular pressure change. In eyes with narrow angles there is a greater drop in intraocular pressure after cataract surgery and it is correlated with parameters related to anterior chamber space. It is safe to affirm that cataract surgery is an important part of the modern glaucoma treatment and evidence should be analyzed as part of a bigger picture in order to more accurately understand its clinical relevance.
白内障摘除术是一种安全有效的手术，可降低眼内压。这种效果的具体机制尚不清楚。对小梁网的直接炎症作用、血房水屏障的改变、睫状体的变化以及前节解剖结构的机械变化是理解白内障手术及其对房水动力学影响的关键。此外，随着 AS-OCT 的出现，人们已经研究了眼球前段的变化，并且已经确定了几个参数（如晶状体拱顶、房角开口距离和前房深度）作为眼压变化的预测指标。在窄角眼，白内障手术后眼压下降幅度更大，并且与前房空间相关参数相关。可以肯定地说，白内障手术是现代青光眼治疗的重要组成部分，应该分析证据作为更大画面的一部分，以便更准确地了解其临床相关性。
