囊胚在子宫内的存在通过上调溶酶体蛋白稳态活性促进腔上皮的转化，从而有利于着床。
The presence of blastocyst within the uteri facilitates lumenal epithelium transformation for implantation via upregulating lysosome proteostasis activity.
机构信息
State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, Beijing, China.
Fujian Provincial Key Laboratory of Reproductive Health Research, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China.
出版信息
Autophagy. 2024 Jan;20(1):58-75. doi: 10.1080/15548627.2023.2247747. Epub 2023 Aug 22.
ACTB
actin beta; AREG: amphiregulin; ATP6V0A4: ATPase, H transporting, lysosomal V0 subunit A4; Baf A1: bafilomycin A; BSA: bovine serum albumin; CLDN1: claudin 1; CTSB: cathepsin B; DEGs: differentially expressed genes; E: 17β-estradiol; ESR: estrogen receptor; GATA2: GATA binding protein 2; GLA: galactosidase, alpha; GO: gene ontology; HBEGF: heparin-binding EGF-like growth factor; IGF1R: insulin-like growth factor 1 receptor; Ihh: Indian hedgehog; ISH: in situ hybridization; LAMP1: lysosomal-associated membrane protein 1; LCM: laser capture microdissection; Le: lumenal epithelium; LGMN: legumain; LIF: leukemia inhibitory factor; LIFR: LIF receptor alpha; MSX1: msh homeobox 1; MUC1: mucin 1, transmembrane; P: progesterone; PBS: phosphate-buffered saline; PCA: principal component analysis; PPT1: palmitoyl-protein thioesterase 1; PGR: progesterone receptor; PSP: pseudopregnancy; PTGS2/COX2: prostaglandin-endoperoxide synthase 2; qPCR: quantitative real-time polymerase chain reaction; SP: pregnancy; TFEB: transcription factor EB.
ACTB
肌动蛋白β；AREG：双调蛋白；ATP6V0A4：ATP 酶，H 转运，溶酶体 V0 亚基 A4；Baf A1：巴佛洛霉素 A；BSA：牛血清白蛋白；CLDN1：紧密连接蛋白 1；CTSB：组织蛋白酶 B；DEGs：差异表达基因；E：17β-雌二醇；ESR：雌激素受体；GATA2：GATA 结合蛋白 2；GLA：α-半乳糖苷酶；GO：基因本体论；HBEGF：肝素结合 EGF 样生长因子；IGF1R：胰岛素样生长因子 1 受体；Ihh：印度刺猬；ISH：原位杂交；LAMP1：溶酶体相关膜蛋白 1；LCM：激光捕获显微切割；Le：管腔上皮；LGMN：组织蛋白酶 L；LIF：白血病抑制因子；LIFR：LIF 受体α；MSX1：MSX 同源盒 1；MUC1：跨膜粘蛋白 1；P：孕酮；PBS：磷酸盐缓冲盐水；PCA：主成分分析；PPT1：棕榈酰蛋白硫酯酶 1；PGR：孕酮受体；PSP：假性妊娠；PTGS2/COX2：前列腺素内过氧化物合酶 2；qPCR：实时定量聚合酶链反应；SP：妊娠；TFEB：转录因子 EB。
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