Department of Biomedical Engineering, Tianjin University, 92 Weijin Road, Tianjin 300072, China.
Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing 100053, China.
Sci Adv. 2023 Aug 18;9(33):eadi5451. doi: 10.1126/sciadv.adi5451. Epub 2023 Aug 16.
Magnetic resonance imaging (MRI)-safe implantable wireless energy harvester offers substantial benefits to patients suffering from brain disorders, hearing impairment, and arrhythmias. However, rigid magnets in cutting-edge systems with limited numbers of rotation axis impose high risk of device dislodgement and magnet failure. Here, a flexible omnidirectional rotating magnetic array (FORMA) and a flexible MRI-safe implantable wireless energy-harvesting system have been developed. Miniaturized flexible magnetic balls 1 millimeter in diameter achieved by molding three-dimensional printed templates can rotate freely in elastomer cavities and supply a magnetic force of 2.14 Newtons at a distance of 1 millimeter between an implantable receiver and a wearable transceiver. The system can work stably under an acceleration of 9 and obtain a power output of 15.62 decibel milliwatts at a transmission frequency of 8 megahertz. The development of the FORMA may lead to life-long flexible and batteryless implantable systems and offers the potential to promote techniques for monitoring and treating acute and chronic diseases.
磁共振成像(MRI)安全植入式无线能量收集器为患有脑部疾病、听力障碍和心律失常的患者带来了巨大的益处。然而,在具有有限旋转轴数量的尖端系统中使用的刚性磁铁会带来很高的设备移位和磁铁失效风险。在这里,开发了一种灵活的全方位旋转磁场阵列(FORMA)和一种灵活的 MRI 安全植入式无线能量收集系统。通过模压三维打印模板制成的直径为 1 毫米的小型化柔性磁球可以在弹性体腔中自由旋转,并在植入式接收器和可穿戴式收发器之间的距离为 1 毫米处提供 2.14 牛顿的磁力。该系统可以在加速度为 9 的情况下稳定工作,并在传输频率为 8 兆赫时获得 15.62 分贝毫瓦的功率输出。FORMA 的发展可能会导致终身灵活且无需电池的植入式系统,并有可能促进监测和治疗急性和慢性疾病的技术。