Vitamin B-reath easier: vitamin B6 derivatives reduce IL-33 to limit lung inflammation.
作者信息
Turnquist Hēth R
机构信息
Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine; Department of Immunology, and Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
出版信息
Cell Mol Immunol. 2023 Dec;20(12):1527-1529. doi: 10.1038/s41423-023-01076-z. Epub 2023 Aug 16.
Abstract
摘要
相似文献
1
Vitamin B-reath easier: vitamin B6 derivatives reduce IL-33 to limit lung inflammation.维生素B让呼吸更轻松：维生素B6衍生物可降低白细胞介素-33以限制肺部炎症。
Cell Mol Immunol. 2023 Dec;20(12):1527-1529. doi: 10.1038/s41423-023-01076-z. Epub 2023 Aug 16.
2
Subclinical inflammation, telomere shortening, homocysteine, vitamin B6, and mortality: the Ludwigshafen Risk and Cardiovascular Health Study.亚临床炎症、端粒缩短、同型半胱氨酸、维生素 B6 和死亡率：路德维希港风险和心血管健康研究。
Eur J Nutr. 2020 Jun;59(4):1399-1411. doi: 10.1007/s00394-019-01993-8. Epub 2019 May 25.
3
Effect of Combined Treatment With Folic Acid, Vitamin B, and Vitamin B on Plasma Biomarkers of Inflammation and Endothelial Dysfunction in Women.叶酸、维生素 B 和维生素 B 联合治疗对女性血浆炎症和内皮功能障碍生物标志物的影响。
J Am Heart Assoc. 2018 May 18;7(11):e008517. doi: 10.1161/JAHA.117.008517.
4
Vitamin B6 inhibits macrophage activation to prevent lipopolysaccharide-induced acute pneumonia in mice.维生素 B6 抑制巨噬细胞活化，预防脂多糖诱导的小鼠急性肺炎。
J Cell Mol Med. 2020 Mar;24(5):3139-3148. doi: 10.1111/jcmm.14983. Epub 2020 Jan 22.
5
Vitamin B6 regulates IL-33 homeostasis to alleviate type 2 inflammation.维生素 B6 通过调节 IL-33 动态平衡缓解 2 型炎症。
Cell Mol Immunol. 2023 Jul;20(7):794-807. doi: 10.1038/s41423-023-01029-6. Epub 2023 May 23.
6
The importance, prevalence and determination of vitamins B6 and B12 in food matrices: A review.食物基质中维生素 B6 和 B12 的重要性、普遍性和测定：综述。
Food Chem. 2023 Nov 15;426:136606. doi: 10.1016/j.foodchem.2023.136606. Epub 2023 Jun 19.
7
Long-Term, Supplemental, One-Carbon Metabolism-Related Vitamin B Use in Relation to Lung Cancer Risk in the Vitamins and Lifestyle (VITAL) Cohort.维生素与生活方式（VITAL）队列研究中，长期补充与一碳代谢相关的维生素B与肺癌风险的关系。
J Clin Oncol. 2017 Oct 20;35(30):3440-3448. doi: 10.1200/JCO.2017.72.7735. Epub 2017 Aug 22.
8
Erythrocyte concentrations of B1, B2, B6 but not plasma C and E are reliable indicators of nutrition status in the presence of systemic inflammation.在存在全身性炎症的情况下，红细胞中维生素B1、B2、B6的浓度而非血浆中维生素C和维生素E的浓度是营养状况的可靠指标。
Clin Nutr ESPEN. 2017 Feb;17:54-62. doi: 10.1016/j.clnesp.2016.10.007. Epub 2016 Nov 17.
9
[Meta-analysis on effect of combined supplementation of folic acid, vitamin B12 and B6 on risk of cardio-cerebrovascular diseases in randomized control trials].[叶酸、维生素B12和B6联合补充对随机对照试验中心脑血管疾病风险影响的Meta分析]
Zhonghua Liu Xing Bing Xue Za Zhi. 2016 Jul;37(7):1028-34. doi: 10.3760/cma.j.issn.0254-6450.2016.07.024.
10
[Quantitative chromatographical determination of vitamin B6 derivatives].
Acta Vitaminol. 1956 Feb;10(1):27-31.
引用本文的文献
1
Per- and polyfluoroalkyl substances (PFAS): immunotoxicity at the primary sites of exposure.全氟和多氟烷基物质（PFAS）：暴露主要部位的免疫毒性。
Crit Rev Toxicol. 2025;55(4):484-504. doi: 10.1080/10408444.2025.2501420. Epub 2025 May 22.
2
FDA-approved drug repurposing screen identifies inhibitors of SARS-CoV-2 pseudovirus entry.美国食品药品监督管理局（FDA）批准的药物重新利用筛选确定了严重急性呼吸综合征冠状病毒2（SARS-CoV-2）假病毒进入的抑制剂。
Front Pharmacol. 2025 Mar 17;16:1537912. doi: 10.3389/fphar.2025.1537912. eCollection 2025.
本文引用的文献
1
Vitamin B6 regulates IL-33 homeostasis to alleviate type 2 inflammation.维生素 B6 通过调节 IL-33 动态平衡缓解 2 型炎症。
Cell Mol Immunol. 2023 Jul;20(7):794-807. doi: 10.1038/s41423-023-01029-6. Epub 2023 May 23.
2
Emerging Functions of IL-33 in Homeostasis and Immunity.IL-33 在稳态和免疫中的新兴功能。
Annu Rev Immunol. 2022 Apr 26;40:15-43. doi: 10.1146/annurev-immunol-101320-124243. Epub 2022 Jan 5.
3
Efficacy and Safety of Itepekimab in Patients with Moderate-to-Severe Asthma.伊特司珠单抗治疗中重度哮喘的疗效和安全性。
N Engl J Med. 2021 Oct 28;385(18):1656-1668. doi: 10.1056/NEJMoa2024257.
4
The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity.泛素连接酶 MDM2 维持 STAT5 的稳定性以控制 T 细胞介导的抗肿瘤免疫。
Nat Immunol. 2021 Apr;22(4):460-470. doi: 10.1038/s41590-021-00888-3. Epub 2021 Mar 25.
5
Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function.鼠双微体 2 同源物介导的泛素化促进叉头框 P3 的稳定性，并正向调节人调节性 T 细胞的功能。
Front Immunol. 2020 Jun 19;11:1087. doi: 10.3389/fimmu.2020.01087. eCollection 2020.
6
Mdm2 is required for HDAC3 monoubiquitination and stability.Mdm2 对于 HDAC3 的单泛素化和稳定性是必需的。
Biochem Biophys Res Commun. 2019 Sep 17;517(2):353-358. doi: 10.1016/j.bbrc.2019.07.052. Epub 2019 Jul 26.
7
Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017.全球、区域和国家按年龄、性别和死因分类的死亡率，195 个国家和地区，1980-2017 年：2017 年全球疾病负担研究的系统分析。
Lancet. 2018 Nov 10;392(10159):1736-1788. doi: 10.1016/S0140-6736(18)32203-7. Epub 2018 Nov 8.
8
Interleukin-33 in health and disease.白细胞介素-33 在健康和疾病中的作用。
Nat Rev Immunol. 2016 Nov;16(11):676-689. doi: 10.1038/nri.2016.95. Epub 2016 Sep 19.
9
Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation.IL-33 的亚细胞定位改变导致非解决性致死性炎症。
J Autoimmun. 2014 Dec;55:33-41. doi: 10.1016/j.jaut.2014.02.012. Epub 2014 Apr 29.
10
Resequencing candidate genes implicates rare variants in asthma susceptibility.重测序候选基因提示罕见变异与哮喘易感性相关。
Am J Hum Genet. 2012 Feb 10;90(2):273-81. doi: 10.1016/j.ajhg.2012.01.008.
Zotero 插件