Spinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, NSW, Australia.
University of New South Wales, Sydney, NSW, Australia.
Spinal Cord. 2023 Sep;61(9):505-512. doi: 10.1038/s41393-023-00920-3. Epub 2023 Aug 16.
Secondary analysis of a randomised controlled trial.
Our primary study showed that increasing inspiratory muscle strength with training in people with chronic (>1 year) tetraplegia corresponded with reduced sensations of breathlessness when inspiration was loaded. This study investigated whether respiratory muscle training also affected the respiratory sensations for load detection and magnitude perception.
Independent research institute in Sydney, Australia.
Thirty-two adults with chronic tetraplegia participated in a 6-week, supervised training protocol. The active group trained the inspiratory muscles through progressive threshold loading. The sham group performed the same protocol with a fixed threshold load (3.6 cmHO). Primary measures were load detection threshold and perceived magnitudes of six suprathreshold loads reported using the modified Borg scale.
Maximal inspiratory pressure (PI) increased by 32% (95% CI, 18-45) in the active group with no change in the sham group (p = 0.51). The training intervention did not affect detection thresholds in the active (p = 0.24) or sham (p = 0.77) group, with similar overall decreases in Borg rating of 0.83 (95% CI, 0.49-1.17) in active and 0.72 (95% CI, 0.32-1.12) in sham group. Increased inspiratory muscle strength reduced slope magnitude between Borg rating and peak inspiratory pressure (p = 0.003), but not when pressure was divided by PI to reflect contraction intensity (p = 0.92).
Training reduces the sensitivity of load sensations for a given change in pressure but not for a given change in contraction intensity.
随机对照试验的二次分析。
我们的初步研究表明，在患有慢性（>1 年）四肢瘫痪的人群中，通过训练增加吸气肌力量与吸气负荷时呼吸困难感的减少有关。本研究旨在探讨呼吸肌训练是否也会影响用于负荷检测和感知幅度的呼吸感觉。
澳大利亚悉尼的独立研究机构。
32 名患有慢性四肢瘫痪的成年人参加了为期 6 周的监督训练方案。实验组通过逐步阈上负荷训练吸气肌。对照组则以固定的阈上负荷（3.6cmHO）进行相同的方案。主要测量指标是使用改良 Borg 量表报告的负荷检测阈值和六个超阈上负荷的感知幅度。
实验组的最大吸气压力（PI）增加了 32%（95%置信区间，18-45），而对照组没有变化（p=0.51）。训练干预对实验组（p=0.24）或对照组（p=0.77）的检测阈值均无影响，实验组的 Borg 评分总体下降了 0.83（95%置信区间，0.49-1.17），对照组下降了 0.72（95%置信区间，0.32-1.12）。吸气肌力量的增加降低了 Borg 评分与最大吸气压力之间的斜率幅度（p=0.003），但当压力除以 PI 以反映收缩强度时则没有影响（p=0.92）。
训练降低了给定压力变化时的负荷感觉敏感性，但不影响给定收缩强度变化时的负荷感觉敏感性。
