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因钙化而进行的无缝线巩膜固定型 Carlevale 人工晶状体取出:临床和实验室报告。

Explantation of a sutureless scleral fixated Carlevale intraocular lens due to calcification: a clinical and laboratory report.

机构信息

Department of Ophthalmology, 251 Hellenic Air Force General Hospital, 16 Avras Str, 166 73, Athens, Greece.

Department of Chemical Engineering, Laboratory of Inorganic and Analytical Chemistry, University of Patras and FORTH/ICE-HT, Patras, Greece.

出版信息

BMC Ophthalmol. 2023 Aug 16;23(1):359. doi: 10.1186/s12886-023-03102-0.

Abstract

BACKGROUND

Hydrophilic intraocular lens opacification is a rare complication due to calcification. With current new surgical techniques, including lamellar endothelial keratoplasty and vitrectomies, this irreversible complication is becoming more common. In this case study, we present clinical and laboratory features of a case of Carlevale hydrophilic acrylic IOL calcification.

CASE PRESENTATION

Observational case report of a single incident case. An 83-year-old man was referred to our ophthalmic department complaining of right eye vision blurring for six months. Slit-lamp biomicroscopy revealed IOL opacification. Deposits of calcium phosphate were found both on the IOL's surface and inside it, according to thorough investigation using optical, scanning electron microscopy (SEM), and energy-dispersive X-ray (EDX) spectrometry.

CONCLUSIONS

To the best of our knowledge, this is the first case to describe the laboratory evidence of Carlevale hydrophilic IOL calcification, suggesting possible explanation mechanisms based on underlying pathology and surgical technique. It reminds us that these findings suggest that physicians should be aware of possible hydrophilic IOL calcification.

摘要

背景

亲水性人工晶状体混浊是一种罕见的钙化引起的并发症。随着目前新的手术技术,包括板层内皮角膜移植术和玻璃体切除术,这种不可逆转的并发症变得越来越常见。在本病例研究中,我们介绍了一例 Carlevale 亲水性丙烯酸人工晶状体钙化的临床和实验室特征。

病例介绍

对单一事件病例的观察性病例报告。一名 83 岁男性因右眼视力模糊六个月而被转至我们的眼科部门。裂隙灯生物显微镜检查显示人工晶状体混浊。彻底的光学、扫描电子显微镜(SEM)和能谱分析(EDX)检查发现,人工晶状体的表面和内部都有磷酸钙沉积。

结论

据我们所知,这是首例描述 Carlevale 亲水性人工晶状体钙化的实验室证据的病例,根据潜在的病理学和手术技术提出了可能的解释机制。这提醒我们,这些发现表明医生应该意识到可能存在亲水性人工晶状体钙化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14cd/10433584/e102c6846a4b/12886_2023_3102_Fig1_HTML.jpg

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