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韩国酒渣鼻患者的心理负担与支付意愿及其与酒渣鼻表型和严重程度的关联:一项多中心横断面研究

Psychological Burden and Willingness to Pay Among Korean Rosacea Patients and Their Association With Rosacea Phenotype and Severity: A Multi-Center Cross-Sectional Study.

作者信息

Woo Yu Ri, Kim Suyeun, Cho Sang Hyun, Kim Hei Sung

机构信息

Department of Dermatology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

出版信息

J Cutan Med Surg. 2023 Nov;27(6):601-607. doi: 10.1177/12034754231194017. Epub 2023 Aug 17.

DOI:10.1177/12034754231194017
PMID:37587799
Abstract

BACKGROUND

Rosacea is a chronic inflammatory disorder that can adversely affect the patient's quality of life (QOL). However, few studies have examined the association between the psychological burden and willingness to pay (WTP) with rosacea features and severity.

OBJECTIVES

The study aimed to determine the overall psychological burden and WTP among Korean rosacea patients and identify factors that may contribute, such as patient demographics, clinical features, and rosacea severity.

METHODS

This prospective cross-sectional study recruited Koreans with rosacea. All were asked to complete a questionnaire on their demographics, rosacea-related symptoms, self-rated severity, dermatology life quality index (DLQI), and WTP. The clinical features were assessed by a board-certified dermatologist. The investigator's global assessment and global flushing severity score (GFSS) were used to determine the clinical severity of rosacea. Multiple regression analysis was conducted to identify factors contributing to the psychological burden and WTP.

RESULTS

Out of 201 rosacea patients, 147 (73.1%) were female, and 54 (26.9%) males, with a median age of 50.1 years. Their median DLQI score was 8 (interquartile range [IQR]): 4.0-13.0). The median WTP per month for the control of rosacea was $100, with relative WTP (WTP/household income per month x 100) being 3.3%. According to the multiple regression model, phymatous change (β = .153, p = .030), DLQI score (β = .152, = .045), and GFSS (β = .154, = .041) contributed most to the WTP.

CONCLUSION

Rosacea patients experience substantial psychological and economic burdens. More vigorous treatment should be performed for those with phyma and severe flushing whose QOL is most severely affected.

摘要

背景

酒渣鼻是一种慢性炎症性疾病,会对患者的生活质量(QOL)产生不利影响。然而,很少有研究探讨心理负担与支付意愿(WTP)与酒渣鼻特征和严重程度之间的关联。

目的

本研究旨在确定韩国酒渣鼻患者的总体心理负担和支付意愿,并确定可能的影响因素,如患者人口统计学特征、临床特征和酒渣鼻严重程度。

方法

这项前瞻性横断面研究招募了患有酒渣鼻的韩国人。所有参与者均被要求完成一份关于其人口统计学、酒渣鼻相关症状、自我评估严重程度、皮肤病生活质量指数(DLQI)和支付意愿的问卷。临床特征由一名获得委员会认证的皮肤科医生进行评估。采用研究者的整体评估和整体潮红严重程度评分(GFSS)来确定酒渣鼻的临床严重程度。进行多元回归分析以确定导致心理负担和支付意愿的因素。

结果

在201名酒渣鼻患者中,147名(73.1%)为女性,54名(26.9%)为男性,中位年龄为50.1岁。他们的中位DLQI评分为8(四分位间距[IQR]:4.0 - 13.0)。控制酒渣鼻每月的中位支付意愿为100美元,相对支付意愿(每月支付意愿/家庭收入×100)为3.3%。根据多元回归模型,鼻赘样改变(β = 0.153,p = 0.030)、DLQI评分(β = 0.152,p = 0.045)和GFSS(β = 0.154,p = 0.041)对支付意愿的影响最大。

结论

酒渣鼻患者承受着巨大的心理和经济负担。对于那些鼻赘和严重潮红且生活质量受影响最严重的患者,应采取更积极的治疗措施。

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