Department of Dermatology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Department of Dermatology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
J Cosmet Dermatol. 2022 Jul;21(7):3053-3058. doi: 10.1111/jocd.14546. Epub 2021 Oct 27.
How diseases associated with skin discoloration affect the quality of life (QoL) has rarely been examined. In this study, we directly compared the QoL and willingness to pay (WTP) among patients with skin disorders associated with facial discoloration.
A single-center, cross-sectional study consisting of patients seeking treatment for facial discoloration was performed. All patients completed the dermatology life quality index (DLQI) and the short form 36 (SF-36) health survey questionnaires. Additionally, information regarding monthly income and the WTP for a complete cure of the affected condition was obtained.
Patients with melasma (58), lentigo (56), postinflammatory hyperpigmentation (5), vitiligo (51), acne-induced erythema (10), and rosacea (31) were enrolled. Vitiligo, acne-induced erythema, and rosacea patients reported significantly worse QoL compared to lentigines or melasma patients as evaluated by DLQI. Using SF-36, rosacea patients were affected mentally the most as they reported the worst mental component scores, and the scores were significantly worse than that of melasma patients (rosacea vs. melisma = 46.5 vs. 52.7, p = 0.007). Vitiligo patients had the worst general health scores. Although there were no differences in the WTP among different diseases, the vitiligo group had the highest percentage of patients willing to pay more than 40% of their monthly income for a complete cure.
The impact on QoL is different among skin diseases associated with facial discoloration. Only vitiligo patients reported worse general health as compared to the general population, explaining the discordance between life quality scores and WTP in these patients.
皮肤色素沉着相关疾病如何影响生活质量（QoL），这一问题很少得到研究。在这项研究中，我们直接比较了面部色素沉着相关皮肤疾病患者的 QoL 和支付意愿（WTP）。
进行了一项单中心、横断面研究，纳入了寻求面部色素沉着治疗的患者。所有患者均完成皮肤病生活质量指数（DLQI）和简明健康调查量表 36 项（SF-36）问卷。此外，还收集了关于月收入和对受影响状况完全治愈的支付意愿的信息。
共纳入了黄褐斑（58 例）、老年斑（56 例）、炎症后色素沉着（5 例）、白癜风（51 例）、痤疮性红斑（10 例）和酒渣鼻（31 例）患者。与老年斑或黄褐斑患者相比，白癜风、痤疮性红斑和酒渣鼻患者的 DLQI 评分表明其 QoL 明显更差。使用 SF-36，酒渣鼻患者受精神影响最大，他们报告的精神成分评分最差，且显著低于黄褐斑患者（酒渣鼻 vs. 黄褐斑=46.5 vs. 52.7，p=0.007）。白癜风患者的总体健康评分最差。尽管不同疾病之间的 WTP 没有差异，但白癜风组中愿意支付超过其月收入 40%以获得完全治愈的患者比例最高。
面部色素沉着相关皮肤病对 QoL 的影响不同。只有白癜风患者报告的总体健康状况比一般人群差，这解释了这些患者生活质量评分和 WTP 之间的不匹配。
