Aljhdali Hessa, Balega Janos, Williams Anthony, Ganesan Raji
Anatomic Pathology Department, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Pan-Birmingham Gynaecological Cancer Centre, City Hospital, Birmingham, United Kingdom.
Case Rep Womens Health. 2023 Aug 3;39:e00532. doi: 10.1016/j.crwh.2023.e00532. eCollection 2023 Sep.
Tubal metastasis from endocervical adenocarcinoma is uncommon and is discovered as an incidental finding on routine sampling of fallopian tubes. In this paper, we present the case of an 81-year-old woman who presented with an adnexal mass during investigations of postmenopausal bleeding. Hysterectomy and bilateral salpingo-oophorectomy with excision of the left adnexal mass were performed, which led to the diagnosis of an incidental HPV-associated endocervical adenocarcinoma with secondary, macroscopic tubal involvement. The patient received adjuvant pelvic radiotherapy and remained well after three months of follow-up, with no evidence of recurrence. Only a few cases of endocervical adenocarcinoma with tubal metastasis have been reported in the literature, which are commonly associated with ovarian, uterine corpus, and/or parametrial tissue involvement. To date, there are only two reported cases of isolated tubal metastasis, and in both cases, tubal involvement was discovered microscopically. Data on the impact of secondary tubal involvement on patient outcomes are limited.
宫颈腺癌的输卵管转移并不常见，通常是在对输卵管进行常规取样时偶然发现的。在本文中，我们报告了一例81岁女性患者，该患者在绝经后出血的检查过程中发现附件包块。进行了子宫切除术、双侧输卵管卵巢切除术并切除了左侧附件包块，最终诊断为偶然发现的与人乳头瘤病毒（HPV）相关的宫颈腺癌伴继发性、肉眼可见的输卵管受累。患者接受了辅助盆腔放疗，随访三个月后情况良好，无复发迹象。文献中仅报道了少数几例宫颈腺癌伴输卵管转移的病例，这些病例通常还伴有卵巢、子宫体和/或宫旁组织受累。迄今为止，仅有两例孤立性输卵管转移的报道，且这两例均是在显微镜下发现输卵管受累。关于继发性输卵管受累对患者预后影响的数据有限。
