Department of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University Kasumi, Hiroshima, Japan.
Department of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Kasumi, Hiroshima, Japan.
JBJS Case Connect. 2023 Aug 17;13(3). doi: 10.2106/JBJS.CC.22.00470. eCollection 2023 Jul 1.
We report a case of Bacillus Calmette-Guérin (BCG) vaccine-induced osteomyelitis of the distal end of the right humerus in a 1-year and 8-month-old girl. The patient was treated with debridement and a 12-month antituberculosis drug. After 3 years of follow-up, no growth disturbances or sequelae were observed.
BCG osteomyelitis is difficult to diagnose because of its rarity. It is important to suspect BCG osteomyelitis based on symptoms and blood tests and to perform PCR testing. Long-term follow-up after treatment is necessary to monitor for recurrence and avoid growth disturbances until epiphyseal line closure occurs.
我们报告了一例 1 岁 8 个月大的女孩右侧肱骨远端因卡介苗(BCG)疫苗引起的骨髓炎。患者接受了清创术和 12 个月的抗结核药物治疗。随访 3 年后,未观察到生长障碍或后遗症。
BCG 骨髓炎因其罕见而难以诊断。根据症状和血液检查怀疑 BCG 骨髓炎,并进行 PCR 检测很重要。治疗后需要长期随访,以监测复发并避免生长障碍,直到骺线闭合。