Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Rotman Research Institute, Baycrest Academy for Research and Education, Toronto, ON, Canada.
Appl Physiol Nutr Metab. 2023 Dec 1;48(12):896-906. doi: 10.1139/apnm-2023-0211. Epub 2023 Aug 17.
Malnutrition is correlated with poor cognition; however, an understanding of the association between nutrition risk, which precedes malnutrition, and cognition is lacking. This study aimed to determine if nutrition risk measured with the SCREEN-8 tool is associated with cognitive performance among cognitively healthy adults aged 55+, after adjusting for demographic and lifestyle covariates. Sex- and age-stratified analyses were also explored. Baseline data from the Canadian Longitudinal Study on Aging was used. Cognition was determined using a 6-measure composite score based on four executive functions and two memory tasks, taking into account age, sex, and education. Multivariable linear regression was performed while adjusting for body mass index (BMI), lifestyle, and health covariates in the entire sample ( = 11 378) and then stratified by sex and age. Approximately half of participants were female (54.5%) aged 65+ (54.1%). Greater nutrition risk was associated with poorer cognitive performance in the entire sample ( = 5.36, = 0.021) and among participants aged 55-64 ( = 5227; = 5.45, = 0.020). Sex differences in lifestyle and health factors associated with cognition were apparent, but nutrition risk was not associated with cognition in sex-stratified models. Based on this analysis, there may be an association between nutrition risk and cognitive performance in older adults. When screening for either cognitive impairment or nutrition risk, complementary assessments for these conditions is warranted, as early intervention may provide benefit.
营养不良与认知能力差有关；然而，对于营养风险（先于营养不良发生）与认知之间的关联，人们的理解还很缺乏。本研究旨在确定使用 SCREEN-8 工具测量的营养风险是否与认知健康的 55 岁以上成年人的认知表现有关，在调整了人口统计学和生活方式协变量后。还探索了按性别和年龄分层的分析。使用了加拿大老龄化纵向研究的基线数据。认知能力通过基于四项执行功能和两项记忆任务的六项综合评分来确定，考虑了年龄、性别和教育程度。在整个样本（n=11378）中，在调整了体重指数（BMI）、生活方式和健康协变量后，进行了多变量线性回归，然后按性别和年龄分层。大约一半的参与者为女性（54.5%），年龄在 65 岁以上（54.1%）。在整个样本中（n=11378；β=5.36，p=0.021）以及年龄在 55-64 岁的参与者中（n=5227；β=5.45，p=0.020），营养风险与认知表现较差有关。与认知相关的生活方式和健康因素的性别差异明显，但在按性别分层的模型中，营养风险与认知无关。基于这项分析，在老年人中，营养风险与认知表现之间可能存在关联。在筛查认知障碍或营养风险时，需要对这些情况进行补充评估，因为早期干预可能会带来益处。
