沙眼衣原体A血清型活菌株（而非经辐照的菌株）对小鼠的眼部致敏作用。
Ocular sensitization of mice by live (but not irradiated) Chlamydia trachomatis serovar A.
作者信息
Colley D G, Goodman T G, Barsoum I S
出版信息
Infect Immun. 1986 Oct;54(1):9-12. doi: 10.1128/iai.54.1.9-12.1986.
Ocular exposure of mice to live elementary bodies of Chlamydia trachomatis serovar A results in immunological sensitization of the mice. This reactivity is manifested by the development of early (5 h) and delayed-type (24 h) dermal reactivity and serovar-specific antibody formation against either live or irradiated (100 kilorads) elementary bodies. Parallel ocular exposure of mice to irradiated elementary bodies does not result in this sensitization. The early and late dermal immune responses induced by ocular exposure to live organisms can be transferred to unexposed mice by serum and lymphoid cell transfers, respectively. It appears that successful murine ocular sensitization by human C. trachomatis serovar A elementary bodies is an ability manifested by live organisms and not by inactivated but antigenic organisms.
将小鼠的眼睛暴露于沙眼衣原体A血清型的活原体中会导致小鼠发生免疫致敏。这种反应性表现为早期（5小时）和迟发型（24小时）皮肤反应的出现以及针对活的或经照射（100千拉德）的原体产生血清型特异性抗体。将小鼠的眼睛平行暴露于经照射的原体不会导致这种致敏。眼睛暴露于活生物体所诱导的早期和晚期皮肤免疫反应可分别通过血清和淋巴细胞转移传递给未暴露的小鼠。看来，人沙眼衣原体A血清型原体成功诱导小鼠眼部致敏是活生物体所表现出的一种能力，而非灭活但具有抗原性的生物体所具有的能力。
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