Department of Plant Biochemistry, Center for Plant Molecular Biology (ZMBP), Eberhard Karls University, Tübingen, Germany.
EMBO J. 2023 Sep 18;42(18):e115113. doi: 10.15252/embj.2023115113. Epub 2023 Aug 18.
Cellular organisms have evolved different strategies to defend themselves against the invasion by viruses. In plants, RNA interference (RNAi) or RNA silencing, which is triggered by virus-derived double-stranded (ds)RNA, is considered the main antiviral defence mechanism. Martínez-Pérez et al have now uncovered an additional plant antiviral pathway, termed by the authors "m A-YTHDF axis," which relies on the modification and subsequent recognition of the viral RNA.
细胞生物进化出不同的策略来抵御病毒的入侵。在植物中，由病毒衍生的双链 RNA(dsRNA)触发的 RNA 干扰 (RNAi) 或 RNA 沉默被认为是主要的抗病毒防御机制。Martínez-Pérez 等人现在发现了一种额外的植物抗病毒途径，作者称之为“m A-YTHDF 轴”，该途径依赖于病毒 RNA 的修饰和随后的识别。
