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食管切除术后食管-气管-支气管瘘的外科治疗。

Surgical treatment of esophago-tracheobronchial fistulas after esophagectomy.

机构信息

Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

Department of Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Dis Esophagus. 2024 Jan 1;37(1). doi: 10.1093/dote/doad054.

Abstract

The aim of this study was to evaluate the surgical treatment of esophago-tracheobronchial fistulas (ETBFs) that occurred after esophagectomy with gastric conduit reconstruction in a tertiary referral center for esophageal surgery. All patients who underwent surgical repair for an ETBF after esophagectomy with gastric conduit reconstruction were included in a tertiary referral center. The primary outcome was successful recovery after surgical treatment for ETBF, defined as a patent airway at 90 days after the surgical fistula repair. Secondary outcomes were details on the clinical presentation, diagnostics, and postoperative course after fistula repair. Between 2007 and 2022, 14 patients who underwent surgical repair for an ETBF were included. Out of 14 patients, 9 had undergone esophagectomy with cervical anastomosis and 5 esophagectomy with intrathoracic anastomosis after which 13 patients had developed anastomotic leakage. Surgical treatment consisted of thoracotomy to cover the defect with a pericardial patch and intercostal flap in 11 patients, a patch without interposition of healthy tissue in 1 patient, and fistula repair via cervical incision with only a pectoral muscle flap in 2 patients. After surgical treatment, 12 patients recovered (86%). Mortality occurred in two patients (14%) due to multiple organ failure. This study evaluated the techniques and outcomes of surgical repair of ETBFs following esophagectomy with gastric conduit reconstruction in 14 patients. Treatment was successful in 12 patients (86%) and generally consisted of thoracotomy and coverage of the defect with a bovine pericardial patch followed by interposition with an intercostal muscle.

摘要

本研究旨在评估在三级食管外科转诊中心接受胃管重建食管切除术(esophagectomy with gastric conduit reconstruction)后发生的食管-气管-支气管瘘(esophago-tracheobronchial fistulas,ETBFs)的手术治疗。所有在三级转诊中心接受胃管重建食管切除术治疗 ETBF 的患者均被纳入本研究。主要结局是 ETBF 手术后成功恢复,定义为手术瘘修复后 90 天气道通畅。次要结局是 ETBF 修复后的临床特征、诊断和术后过程的详细信息。2007 年至 2022 年期间,共有 14 例患者接受了 ETBF 手术修复。14 例患者中,9 例接受了颈吻合术,5 例接受了胸内吻合术,其中 13 例发生吻合口漏。手术治疗包括 11 例患者采用心包补片和肋间肌瓣覆盖缺损,1 例患者采用无健康组织间隔的补片,2 例患者仅采用颈切口和胸大肌瓣修复瘘口。手术后,12 例患者(86%)恢复(recovery)。2 例患者(14%)因多器官衰竭死亡。本研究评估了 14 例患者胃管重建食管切除术(esophagectomy with gastric conduit reconstruction)后 ETBF 手术修复的技术和结果。12 例患者(86%)治疗成功,通常采用开胸术并用牛心包补片覆盖缺损,然后用肋间肌进行间隔。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f261/10762505/1832964d600c/doad054f1.jpg

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