Shihadeh Sammy, Stephenson-Moe Christoph A, Vesco Paul, Marshall M Blair
Clinical Sciences, Florida State University College of Medicine, Tallahassee, USA.
Department of Cardiothoracic Surgery, Sarasota Memorial Health Care System, Sarasota, USA.
Cureus. 2025 Jun 13;17(6):e85937. doi: 10.7759/cureus.85937. eCollection 2025 Jun.
Bronchoesophageal fistula (BEF) is a severe complication of esophagectomy and is burdened by high mortality rates, which has scarce reporting in the literature. These fistulas are usually the result of a prior leak from esophagogastric anastomosis. The etiology of a BEF after esophagectomy can be multifactorial. BEF occurrence can be further complicated by a history of esophageal malignancy, predisposing the patient to fistula formation. We present a 71-year-old male with a history of esophageal cancer, treated initially with neoadjuvant chemoradiation and an Ivor-Lewis esophagectomy five months later, discharged on post-operative day six, who had subsequent clinical symptoms, primarily respiratory in nature, two weeks later. Imaging and workup revealed a BEF. After the patient was admitted, he was taken to the operating room (OR) for initial lysis of adhesions and clearance of necrotic tissue and aspiration of secretions. For approximately the next month, every four to five days, he was taken back to the OR for endoluminal sponge vacuum-assisted closure (VAC) placement and replacement as well as additional therapeutic aspiration of secretions, which were often purulent. As the patient was critically ill, this was determined to be the best course of action in the initial stabilization of the BEF as a bridging measure until definitive surgical management could be intervened. This was done in order to promote initial healing of the fistula to optimize tissue for surgical treatment (i.e., supported by presence of granulation tissue). The patient recuperated between procedures in the intensive care unit (ICU). Ultimately, the patient underwent surgical repair and esophageal exclusion. The patient was discharged on post-operative day 60 after recovery and continues seeing his primary care physician and the surgical groups who managed his care to assess for changes in symptoms and follow-up imaging. This case conveys the urgency of diagnosing and treating a BEF, demonstrating improved outcomes when surgically managed in a timely manner.
支气管食管瘘(BEF)是食管切除术的一种严重并发症,死亡率很高,文献报道较少。这些瘘通常是食管胃吻合口先前渗漏的结果。食管切除术后BEF的病因可能是多因素的。BEF的发生可能因食管癌病史而进一步复杂化,使患者易发生瘘的形成。我们报告一名71岁男性,有食管癌病史,最初接受新辅助放化疗,五个月后行Ivor-Lewis食管切除术,术后第六天出院,两周后出现主要为呼吸道性质的临床症状。影像学检查和检查发现了BEF。患者入院后,被送往手术室(OR)进行初始粘连松解、坏死组织清除和分泌物抽吸。在接下来的大约一个月里,每四到五天,他就被带回手术室进行腔内海绵真空辅助闭合(VAC)放置和更换,以及额外的分泌物治疗性抽吸,分泌物通常是脓性的。由于患者病情危重,这被确定为在BEF初始稳定阶段作为过渡措施的最佳行动方案,直到可以进行确定性手术治疗。这样做是为了促进瘘的初步愈合,优化组织以进行手术治疗(即有肉芽组织支持)。患者在重症监护病房(ICU)的两次手术之间康复。最终,患者接受了手术修复和食管旷置术。患者在术后60天康复出院,继续看他原来的初级保健医生以及负责他治疗的外科团队,以评估症状变化和进行后续影像学检查。这个病例传达了诊断和治疗BEF的紧迫性,表明及时进行手术治疗可改善预后。