Zheng Haoqian, Guo Chenyang, Zhang Yadi, Gu Hang, Zhao Yinzhi, Xiang Run, Dai Wei, Wei Xing, Xie Tianpeng, Li Qiang, Wang Xiang
Department of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Center, Sichuan Cancer Hospital & Institute, School of Medicine, University of Electronic Science and Technology of China, No. 55, Section 4, South Renmin Road, Chengdu, 610041, China.
Department of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Graduate School, Sichuan Cancer Hospital, Chengdu Medical College, Chengdu, Sichuan, China.
J Cardiothorac Surg. 2025 Apr 22;20(1):217. doi: 10.1186/s13019-025-03430-w.
The incidence of tracheoesophageal fistula (TEF) following esophagectomy is less than 3%, but it often leads to severe complications and can even be life-threatening to patients. Surgical repair methods for TEF include muscle or omental flap support, biologic patch repair, and sleeve resection. In recent years, there has been an increasing number of case reports on primary closure via a cervical incision, with a rising success rate and a lower incidence of postoperative complications.
A case is presented involving a 68-year-old female patient with esophageal squamous cell carcinoma who underwent thoracoscopic McKeown esophagectomy combined with gastric conduit reconstruction. On postoperative day 10, the patient presented with severe coughing. Gastroscopy and bronchoscopy confirmed a tracheoesophageal fistula at the anastomotic site. After 2 weeks of anti-infective therapy, drainage, and nutritional support, the fistula persisted. Subsequently, an exploratory surgery was performed via the original cervical incision, and the fistula was repaired with primary suture. The patient received routine dressing changes and continued anti-infective therapy postoperatively. One week later, gastroscopy and bronchoscopy revealed complete healing of the trachea, with closure of the anastomotic fistula, and no abnormalities were detected upon oral intake.
This case demonstrates that in patients identified early, with complete drainage, adequate anti-infection measures, and improved nutritional status, primary closure of the tracheoesophageal junction through the original cervical incision can successfully treat an anastomotic trachea-fistula following esophagectomy. Our report details the process of primary repair of TEF through the cervical approach, contributing additional references to existing literature.
食管切除术后气管食管瘘(TEF)的发生率低于3%,但常导致严重并发症,甚至可能危及患者生命。TEF的手术修复方法包括肌肉或网膜瓣支撑、生物补片修复和袖状切除术。近年来,经颈部切口一期缝合的病例报告越来越多,成功率不断提高,术后并发症发生率降低。
本文报告1例68岁女性食管鳞状细胞癌患者,接受了胸腔镜McKeown食管切除术并联合胃代食管重建术。术后第10天,患者出现剧烈咳嗽。胃镜和支气管镜检查证实吻合口处存在气管食管瘘。经过2周的抗感染治疗、引流和营养支持后,瘘口仍未愈合。随后,经原颈部切口进行了探查手术,瘘口采用一期缝合修复。术后患者接受常规换药并继续抗感染治疗。1周后,胃镜和支气管镜检查显示气管完全愈合,吻合口瘘闭合,经口进食未发现异常。
该病例表明,对于早期发现、充分引流、采取充分抗感染措施且营养状况改善的患者,经原颈部切口一期缝合气管食管交界部可成功治疗食管切除术后的吻合口气管瘘。我们的报告详细介绍了经颈部入路一期修复TEF的过程,为现有文献增添了参考资料。