Allen Loyd V
International Journal of Pharmaceutical Compounding.
Int J Pharm Compd. 2023 Jul-Aug;27(4):295-302.
This article, which is part 1 of a series on compounding with antioxidants, discusses specific preparation methods and techniques along with packaging, storing, and labeling issues. Also presented are the allowable overages from the United States Pharmacopeia's discussion on "Commercial Parenteral Products". Some considerations related to potential issues when compounding with commercial products are also discussed using specific examples. The article ends with a discussion of product standardization and look-alike products. The formulation of an antioxidant system is accomplished primarily through trial and error. With some experimentation and patience, a suitable, stable system with the required characteristics can be obtained.
本文是关于抗氧化剂复方制剂系列文章的第1部分,讨论了具体的制备方法和技术以及包装、储存和标签问题。还介绍了美国药典关于“商业注射用产品”讨论中的允许超量。文中还通过具体示例讨论了与商业产品复方制剂时潜在问题的一些注意事项。文章最后讨论了产品标准化和相似产品。抗氧化剂系统的配方主要通过反复试验来完成。经过一些实验并保持耐心,就可以获得具有所需特性的合适、稳定的系统。