Guella Adnane, Muhammad Rabab Zaka, Aljallabi Mahdi, Mursi Abeer, Elmahi Mohamed
University Hospital, Department of Internal Medicine, Sharjah, United Arab Emirates.
University Hospital, Department of Emergency Medicine, Sharjah, United Arab Emirates.
Clin Pract Cases Emerg Med. 2023 Aug;7(3):161-164. doi: 10.5811/cpcem.1545.
Acute focal bacterial nephritis is an underdiagnosed condition. It clinically resembles acute pyelonephritis. If unrecognized and undertreated, it may progress into complications (kidney abscess and scars). Contrast-enhanced computed tomography (CT) reveals specific images of the disease and is considered the gold standard to make the diagnosis.
A 63-year-old male patient with solitary kidney presented with symptoms compatible with acute pyelonephritis. Kidney ultrasound was not conclusive. Because of persisting high-grade fever not resolving after 48 hours of antibiotics, a contrast-enhanced CT was then performed, and the diagnosis of acute focal bacterial nephritis was made. A repeat CT after three weeks of intravenous (IV) antibiotics showed marked improvement of the intrarenal lesions, and a fourth week of IV antibiotics was dispensed.
Diagnosing acute focal bacterial nephritis is important (particularly in a patient with solitary kidney). This will dictate the therapy duration. Unlike acute pyelonephritis, acute focal bacterial nephritis requires at least three weeks duration of antibiotics to avoid progress into further complications.
急性局灶性细菌性肾炎是一种易被漏诊的疾病。其临床表现类似于急性肾盂肾炎。若未被识别和治疗,可能会进展为并发症(肾脓肿和瘢痕)。对比增强计算机断层扫描(CT)可显示该疾病的特定图像,被认为是做出诊断的金标准。
一名63岁的单肾男性患者出现了与急性肾盂肾炎相符的症状。肾脏超声检查结果不明确。由于在使用抗生素48小时后持续高热未消退,随后进行了对比增强CT检查,并确诊为急性局灶性细菌性肾炎。静脉注射(IV)抗生素三周后复查CT显示肾内病变有明显改善,于是又给予了第四周的静脉抗生素治疗。
诊断急性局灶性细菌性肾炎很重要(尤其是对于单肾患者)。这将决定治疗疗程。与急性肾盂肾炎不同,急性局灶性细菌性肾炎需要至少三周的抗生素治疗疗程以避免进展为进一步的并发症。