Department of Neurology with Institute of Translational Neurology, University Hospital Muenster, Muenster, Germany; Institute for Biomagnetism and Biosignal Analysis, University Hospital Muenster, Muenster, Germany.
Department of Speech Language Therapy, School of Health Rehabilitation Sciences, University of Patras, Patras, Achaia, Greece; Centre for Gastrointestinal Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Manchester Academic Health Sciences Centre (MAHSC), Manchester, UK.
Lancet Neurol. 2023 Sep;22(9):858-870. doi: 10.1016/S1474-4422(23)00153-9.
Dysphagia is a major complication following an acute stroke that affects the majority of patients. Clinically, dysphagia after stroke is associated with increased risk of aspiration pneumonia, malnutrition, mortality, and other adverse functional outcomes. Pathophysiologically, dysphagia after stroke is caused by disruption of an extensive cortical and subcortical swallowing network. The screening of patients for dysphagia after stroke should be provided as soon as possible, starting with simple water-swallowing tests at the bedside or more elaborate multi-consistency protocols. Subsequently, a more detailed examination, ideally with instrumental diagnostics such as flexible endoscopic evaluation of swallowing or video fluoroscopy is indicated in some patients. Emerging diagnostic procedures, technical innovations in assessment tools, and digitalisation will improve diagnostic accuracy in the future. Advances in the diagnosis of dysphagia after stroke will enable management based on individual patterns of dysfunction and predisposing risk factors for complications. Progess in dysphagia rehabilitation are essential to reduce mortality and improve patients' quality of life after a stroke.
吞咽障碍是急性脑卒中的主要并发症,影响大多数患者。临床上,脑卒中后吞咽障碍与误吸性肺炎、营养不良、死亡率和其他不良功能结局的风险增加有关。从病理生理学角度来看,脑卒中后吞咽障碍是由于广泛的皮质和皮质下吞咽网络的破坏所致。脑卒中后吞咽障碍患者的筛查应尽快进行,从床边简单的饮水吞咽测试或更复杂的多稠度协议开始。随后,一些患者需要更详细的检查,理想情况下需要使用仪器诊断,如吞咽灵活内镜评估或视频透视。新兴的诊断程序、评估工具的技术创新和数字化将提高未来的诊断准确性。脑卒中后吞咽障碍诊断方面的进展将使管理能够基于功能障碍的个体模式和并发症的易患风险因素。吞咽障碍康复方面的进展对于降低死亡率和改善脑卒中后患者的生活质量至关重要。