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中风后吞咽困难长期管理策略指南中的差距。

Gaps in Guidelines on Long-Term Management Strategies for Post-Stroke Dysphagia.

作者信息

Karisik Anel, Labeit Bendix, Schiefecker Alois Josef, Sollereder Simon, Galvan Oliver, Graf Simone, Kiechl Stefan, Knoflach Michael, Mayer-Suess Lukas

机构信息

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Department of Neurology, Medical Faculty and University Hospital Duesseldorf, Duesseldorf, Germany.

出版信息

Eur J Neurol. 2025 Aug;32(8):e70307. doi: 10.1111/ene.70307.

Abstract

BACKGROUND

Post-stroke dysphagia (PSD) is a frequent yet overlooked complication of stroke with significant implications for rehabilitation. While international guidelines provide structured recommendations for early screening and management, guidance on long-term care remains inconsistent. This position paper synthesizes existing guidelines, identifies critical gaps, and highlights the need for standardized long-term management strategies.

METHODS

Guidelines on PSD management were identified through a two-step approach. Fourteen guidelines were included from a previous systematic review (2014-2023), and two additional guidelines were identified through a systematic PubMed search (2014-2025). Inclusion criteria mandated guidelines of moderate-to-high quality (AGREE II assessment) that were published in peer-reviewed journals and provided specific recommendations for managing PSD during acute, subacute, and chronic phases.

RESULTS

Analysis of 10 moderate-to-high quality guidelines revealed strong consensus on acute-phase screening and early interventions. All recommend dysphagia screening within 24 h of admission, with nine advising nil-per-os status until screening completion. There is consensus on instrumental assessments (videofluoroscopy, endoscopy), though application criteria vary. Management strategies include dietary modifications, nutritional support, oral health care, behavioral interventions, neurostimulation, and pharmacological therapies. While acute-phase recommendations are well defined, structured long-term follow-up guidance remains limited, with only one guideline specifying reassessment intervals beyond hospital discharge.

CONCLUSION

The absence of standardized long-term PSD management likely reflects limited availability of high-quality evidence on long-term care. Further research is needed to establish optimal reassessment intervals, high-risk subgroups, and long-term rehabilitation strategies to improve care for stroke survivors with persistent dysphagia.

摘要

背景

卒中后吞咽困难(PSD)是卒中常见但常被忽视的并发症,对康复有重大影响。虽然国际指南为早期筛查和管理提供了结构化建议,但长期护理方面的指导仍不一致。本立场文件综合了现有指南,确定了关键差距,并强调了标准化长期管理策略的必要性。

方法

通过两步法确定PSD管理指南。从先前的系统评价(2014 - 2023年)中纳入了14项指南,并通过PubMed系统检索(2014 - 2025年)确定了另外两项指南。纳入标准要求为发表在同行评审期刊上的中高质量(AGREE II评估)指南,并提供在急性、亚急性和慢性阶段管理PSD的具体建议。

结果

对10项中高质量指南的分析显示,在急性期筛查和早期干预方面有强烈共识。所有指南都建议在入院24小时内进行吞咽困难筛查,其中9项建议在筛查完成前禁食。在仪器评估(视频荧光吞咽造影、内镜检查)方面存在共识,尽管应用标准有所不同。管理策略包括饮食调整、营养支持、口腔卫生护理、行为干预、神经刺激和药物治疗。虽然急性期建议明确,但结构化的长期随访指导仍然有限,只有一项指南规定了出院后的重新评估间隔。

结论

缺乏标准化的PSD长期管理可能反映了长期护理高质量证据的可用性有限。需要进一步研究以确定最佳重新评估间隔、高危亚组和长期康复策略,以改善对持续性吞咽困难的卒中幸存者的护理。

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