K-252a，一种源自微生物的蛋白激酶C强效抑制剂。
K-252a, a potent inhibitor of protein kinase C from microbial origin.
作者信息
Kase H, Iwahashi K, Matsuda Y
出版信息
J Antibiot (Tokyo). 1986 Aug;39(8):1059-65. doi: 10.7164/antibiotics.39.1059.
PMID:3759657
Abstract
K-252a, a metabolite isolated from the culture broth of Nocardiopsis sp. K-252a, was found to exhibit an extremely potent inhibitory activity on protein kinase C. The IC50 value was 32.9 nM.
摘要
K-252a是从诺卡氏菌属菌株K-252a的培养液中分离出的一种代谢产物，发现它对蛋白激酶C具有极强的抑制活性。半数抑制浓度（IC50）值为32.9纳摩尔。
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