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经外周导入中心静脉置管在癌症患者中的应用:一项随机多中心研究。

Implementation of Tunneled Peripherally Inserted Central Catheters Placement in Cancer Patients: A Randomized Multicenter Study.

机构信息

School of Nursing and Rehabilitation, Shandong University, Jinan, China.

Medical School, Liaocheng University, China.

出版信息

Clin Nurs Res. 2024 Jan;33(1):19-26. doi: 10.1177/10547738231194099. Epub 2023 Aug 19.

DOI:10.1177/10547738231194099
PMID:37596863
Abstract

This study sought to evaluate the impact of the subcutaneous tunneling technique on peripherally inserted central catheter (PICC) placement. We randomized 694 patients who needed PICC placement to either the tunneled PICCs (experimental group) or the non-tunneled PICCs (control group) from August to December 2021. The cumulative frequency of complications was assessed as the primary outcome. Secondary outcomes comprised of the amount of bleeding, catheter insertion time, self-reported pain score, and one-puncture success rate. After 6 months of follow-up, the tunneled PICCs group showed a significant decrease in the frequency of total complications, especially in infection (3.0% vs. 7.1%,  = .021) and catheter-related thrombosis (3.3% vs. 8.3%,  = .008), although approximately 0.5 ml bleeding and 3.5 min time were increased. This randomized multicenter study supports the efficacy of subcutaneous tunneling technology in reducing PICC-related complications, enhancing patient comfort, and encouraging using subcutaneous tunneling technology for PICC placement.

摘要

本研究旨在评估皮下隧道技术对经外周中心静脉置管(PICC)置管的影响。我们于 2021 年 8 月至 12 月将 694 例需要 PICC 置管的患者随机分为隧道式 PICC(实验组)和非隧道式 PICC(对照组)。并发症的累积频率被评估为主要结局。次要结局包括出血量、导管插入时间、自我报告疼痛评分和一次穿刺成功率。随访 6 个月后,隧道式 PICC 组的总并发症发生率显著降低,尤其是感染(3.0% vs. 7.1%,=0.021)和导管相关性血栓形成(3.3% vs. 8.3%,=0.008),尽管出血增加约 0.5ml,插入时间延长 3.5 分钟。这项随机多中心研究支持皮下隧道技术在降低 PICC 相关并发症、提高患者舒适度方面的有效性,并鼓励将皮下隧道技术用于 PICC 置管。

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引用本文的文献

1
Prevention of Peripherally Inserted Central Catheter (PICC)-Associated Vein Thrombosis in Cancer: A Narrative Review.癌症患者中预防经外周静脉穿刺中心静脉置管(PICC)相关静脉血栓形成:一项叙述性综述
Biomedicines. 2025 Mar 24;13(4):786. doi: 10.3390/biomedicines13040786.
2
Complications of tunneled and non-tunneled peripherally inserted central catheter placement in chemotherapy-treated cancer patients: a meta-analysis.化疗癌症患者经隧道式和非隧道式外周静脉穿刺中心静脉置管的并发症:一项荟萃分析。
Front Surg. 2024 Oct 15;11:1469847. doi: 10.3389/fsurg.2024.1469847. eCollection 2024.
3
A case report on the choice of venous access after ectopic peripherally inserted central catheter in an upper limb of a patient with a second recurrence of right-side breast cancer.
右侧乳腺癌第二次复发患者上肢外周静脉穿刺中心静脉置管异位后静脉通路选择的病例报告。
Medicine (Baltimore). 2024 Oct 25;103(43):e40104. doi: 10.1097/MD.0000000000040104.
4
Brachial Tunneled Peripherally Inserted Central Catheters and the Risk of Catheter Complications: A Systematic Review and Meta-Analysis.肱静脉隧道式外周静脉穿刺中心静脉导管与导管相关并发症风险:一项系统评价和荟萃分析
Nurs Rep. 2024 Feb 18;14(1):455-467. doi: 10.3390/nursrep14010035.