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内镜治疗藏毛窦疾病 5 年后复发:多中心经验。

Five-year recurrence after endoscopic approach to pilonidal sinus disease: A multicentre experience.

机构信息

Department of Advanced Biomedical Sciences, "Federico II" University of Naples, Naples, Italy.

Department of Clinical Medicine and Surgery, "Federico II" University of Naples, Naples, Italy.

出版信息

Tech Coloproctol. 2023 Oct;27(10):929-935. doi: 10.1007/s10151-023-02846-7. Epub 2023 Aug 19.

Abstract

PURPOSE

The aim of this study was to evaluate the 5-year recurrence rate of pilonidal sinus disease (PSD) after endoscopic sinusectomy and identify risk factors for recurrence.

METHODS

All consecutive patients from September 2011 through December 2017 who underwent endoscopic sinusectomy at seven referral centres for pilonidal sinus treatment were retrospectively analysed from a prospectively maintained database.

RESULTS

Out of 290 patients (185 males versus 105 female, with a mean age of 25.5±6.9), 73 presented recurrence at 5-year follow-up with a recurrence rate of 25.2%. The number of pilonidal sinus with pits off the midline (p = 0.001) and the mean (SD) distance from the most lateral orifice to the midline (p = 0.001) were higher in the group of patients with recurrence at 5-year follow-up. Multivariate analysis demonstrated that the position of the pits off the midline (p = 0.001) and the distance of the most lateral orifice from the midline (p = 0.001) were independent risk factors for recurrence at 5-year follow-up. Receiver operating characteristic (ROC) curve analysis showed that the distance of lateral orifice from midline predicted an 82.2% possibility of recurrence at 5-year follow-up and Youden's test identified the best cut-off as 2 cm for this variable. Out of 195 cases with the most lateral orifice less than 2 cm from the midline, 13 presented recurrence at 5-year follow-up with a recurrence rate of 6.7%. Out of 95 cases with the most lateral orifice more than 2 cm from midline, 60 showed recurrence at 5-year follow-up with a recurrence rate of 63.2%.

CONCLUSIONS

This data may help guide which disease characteristics predict the optimal use of an endoscopic pilonidal sinus technique.

摘要

目的

本研究旨在评估内镜鼻窦切除术治疗后皮瓣窦疾病(PSD)的 5 年复发率,并确定复发的风险因素。

方法

回顾性分析了 2011 年 9 月至 2017 年 12 月期间在 7 个皮瓣窦治疗转诊中心接受内镜鼻窦切除术的所有连续患者,这些患者来自一个前瞻性维护的数据库。

结果

在 290 名患者中(185 名男性与 105 名女性,平均年龄 25.5±6.9),73 名患者在 5 年随访时出现复发,复发率为 25.2%。在 5 年随访时复发的患者中,中线以外的皮瓣窦数量(p=0.001)和最外侧孔到中线的平均(SD)距离(p=0.001)更高。多变量分析表明,中线以外的窦口位置(p=0.001)和最外侧孔到中线的距离(p=0.001)是 5 年随访时复发的独立风险因素。接收者操作特征(ROC)曲线分析表明,外侧孔到中线的距离预测 5 年随访时复发的可能性为 82.2%,约登测试确定该变量的最佳截止值为 2cm。在 195 例最外侧孔距中线小于 2cm 的病例中,有 13 例在 5 年随访时复发,复发率为 6.7%。在 95 例最外侧孔距中线大于 2cm 的病例中,有 60 例在 5 年随访时复发,复发率为 63.2%。

结论

这些数据可能有助于指导哪些疾病特征预测内镜皮瓣窦技术的最佳应用。

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