Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.
School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Diabet Med. 2024 Mar;41(3):e15206. doi: 10.1111/dme.15206. Epub 2023 Sep 2.
This population-based study sought to explore in detail the conditions driving the diversification in causes of death among people with diabetes.
We linked Australians with type 1 or type 2 diabetes of all ages on the National Diabetes Services Scheme to the National Death Index for 2002-2019. We investigated the proportional contributions of different causes of death to total deaths over time across eight categories of causes of death, stratified by sex and diabetes type. The underlying causes of death were classified according to the International Classification of Diseases, Tenth Revision codes.
Between 2002 and 2019, there was a shift in the causes of death among Australians with diabetes away from cardiovascular disease. The proportion of deaths attributed to cardiovascular disease declined in both sexes (p <0.001), most substantially among women with type 2 diabetes from 48.2% in 2002 to 30.7% in 2019. Among men with type 2 diabetes, cancer replaced cardiovascular disease as the leading cause of death. The proportion of deaths due to dementia increased overall, from 2% in 2002 to over 7% in 2019, and across all age groups, notably from 1% to 4% in those aged 70-79. The proportion of deaths due to falls and Parkinson's disease also increased.
There has been a shift of causes of death among those with diabetes away from cardiovascular disease. The proportion of deaths due to conditions such as dementia and falls is increasing among those with diabetes, which will require consideration when planning future resource allocation.
本基于人群的研究旨在详细探讨导致糖尿病患者死亡原因多样化的因素。
我们将所有年龄段的 1 型或 2 型糖尿病患者纳入国家糖尿病服务计划,并将其与 2002 年至 2019 年的国家死亡索引相关联。我们调查了不同死亡原因在 8 个死亡原因类别中随时间变化对总死亡人数的比例贡献,按性别和糖尿病类型进行分层。根据国际疾病分类第十版代码对死亡的根本原因进行分类。
在 2002 年至 2019 年间,澳大利亚糖尿病患者的死亡原因发生了转变,心血管疾病的比例有所下降。在两性中,心血管疾病导致的死亡比例均有所下降(p<0.001),2 型糖尿病女性下降幅度最大,从 2002 年的 48.2%下降至 2019 年的 30.7%。在 2 型糖尿病男性中,癌症取代心血管疾病成为主要死因。痴呆导致的死亡比例总体上升,从 2002 年的 2%上升至 2019 年的 7%以上,在所有年龄组中,尤其是在 70-79 岁年龄组中,从 1%上升至 4%。跌倒和帕金森病导致的死亡比例也有所增加。
糖尿病患者的死亡原因已经从心血管疾病转移。痴呆和跌倒等疾病导致的死亡比例在糖尿病患者中正在增加,这在规划未来资源分配时需要考虑。