Department of Liver Surgery and Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu, China.
Biosci Trends. 2023 Nov 18;17(5):325-334. doi: 10.5582/bst.2023.01152. Epub 2023 Aug 19.
Hepatic hemangioma, focal nodular hyperplasia, and hepatic adenoma are the most common benign solid liver tumors. However, their surgical indications have been the subject of debate. Minimally invasive liver resection reduces the cost of surgery and may lead to overtreatment of benign liver tumors. Recently, there has been a growing understanding of the etiology, pathogenesis, and natural history of these tumors. Great progress has also been made in imaging. The use of MRI and contrast agents has improved the accuracy of non-invasive diagnosis of these tumors, and especially in the identification of specific molecular subtypes of liver adenoma. These factors have resulted in alterations of surgical indications for these tumors. This article examines recent literature and it discusses the surgical indications for hepatic hemangioma, focal nodular hyperplasia, and hepatic adenoma while summarizing modifications in clinical management.
肝血管瘤、局灶性结节性增生和肝腺瘤是最常见的良性肝脏实性肿瘤。然而，它们的手术适应证一直存在争议。微创肝切除术降低了手术费用，可能导致良性肝肿瘤的过度治疗。最近，人们对这些肿瘤的病因、发病机制和自然史有了更深入的了解。影像学也取得了很大的进展。MRI 和造影剂的应用提高了这些肿瘤无创诊断的准确性，特别是在肝腺瘤特定分子亚型的鉴别诊断方面。这些因素导致了这些肿瘤手术适应证的改变。本文查阅了近期文献，讨论了肝血管瘤、局灶性结节性增生和肝腺瘤的手术适应证，并总结了临床处理的改变。
