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[大语言模型在重症医学中的应用与挑战]

[Applications and challenges of large language models in critical care medicine].

作者信息

Su L X, Weng L, Li W X, Long Y

机构信息

Department of Critical Care Medicine, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.

Medical Intensive Care Unit, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2023 Aug 22;103(31):2361-2364. doi: 10.3760/cma.j.cn112137-20230524-00847.

Abstract

The rapid development of big data methods and technologies has provided more and more new ideas and methods for clinical diagnosis and treatment. The emergence of large language models (LLM) has made it possible for human-computer interactive dialogues and applications in complex medical scenarios. Critical care medicine is a process of continuous dynamic targeted treatment. The huge data generated in this process needs to be integrated and optimized through models for clinical application, interaction in teaching simulation, and assistance in scientific research. Using the LLM represented by generative pre-trained transformer ChatGPT can initially realize the application in the diagnosis of severe diseases, the prediction of death risk and the management of medical records. At the same time, the time and space limitations, illusions and ethical and moral issues of ChatGPT emerged as the times require. In the future, it is undeniable that it may play a huge role in the diagnosis and treatment of critical care medicine, but the current application should be combined with more clinical knowledge reserves of critical care medicine to carefully judge its conclusions.

摘要

大数据方法和技术的快速发展为临床诊断和治疗提供了越来越多的新思路和方法。大语言模型(LLM)的出现使得人机交互对话以及在复杂医疗场景中的应用成为可能。重症医学是一个持续动态靶向治疗的过程。在此过程中产生的海量数据需要通过模型进行整合和优化,以用于临床应用、教学模拟中的交互以及科研辅助。使用以生成式预训练变换器ChatGPT为代表的大语言模型能够初步实现其在重症疾病诊断、死亡风险预测以及病历管理方面的应用。与此同时,ChatGPT的时空局限性、幻觉以及伦理道德问题也应运而生。未来,不可否认它可能在重症医学的诊断和治疗中发挥巨大作用,但当前的应用应结合更多重症医学的临床知识储备,谨慎判断其结论。

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