乳腺癌化疗女性的足部健康和生活质量：一项横断面研究。

Foot health and quality of life in women with breast cancer undergoing chemotherapy: a cross-sectional study.

机构信息

Department of Health Sciences, Faculty of Nursing and Podiatry, Universidade da Coruña, Campus Esteiro, Ferrol, 15471, Spain.

Research Group in Nursing and Health Care, Instituto de Investigación Biomédica de A Coruña (INIBIC), Hospital Universitario de A Coruña (HUAC), Sergas, Universidade da Coruña (UDC), A Coruña, 15006, Spain.

出版信息

J Foot Ankle Res. 2023 Aug 21;16(1):52. doi: 10.1186/s13047-023-00650-y.

DOI:10.1186/s13047-023-00650-y

PMID:37599367

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10440865/

Abstract

BACKGROUND

Chemotherapy is one of the most widely used therapies for breast cancer, triggering important repercussions on people's quality of life. However, little research has been undertaken about podiatric adverse effects. This study aimed was to determine the prevalence of podiatric pathology developed in people with breast cancer who receive chemotherapy.

METHODS

Observational, descriptive, and cross-sectional study was conducted in the Oncology service of the A Coruña University Hospital (northwest Spain). People with breast cancer and undergoing chemotherapy treatment of legal age (≥ 18), who signed the informed consent (n = 117) were included. Sociodemographic, comorbidity, disease and foot health variables, as well as two self-administered questionnaires (Foot Health Status Questionnaire and Foot Function Index) were studied. The current ethical-legal aspects were followed.

RESULTS

Foot health problems were highly prevalent, highlighting nail color changes (59.8%), onychocryptosis (39.7%), xerosis (62.4%), plantar fasciitis (12.8%), and neuropathic symptoms (75.2%). Some foot pain was presented in 77.8% of the sample, predominantly at nail level (15.4%) or sole of the foot and nail (14.5%). Most participants described their foot health as fair or poor (56.4%) and felt limited in walking (65.8%). The lowest score for the Foot Health Status Questionnaire was footwear (30.6(33.5)).

CONCLUSIONS

Foot health adverse effects represent worrisome problems in women with breast cancer undergoing chemotherapy, due to their high prevalence and negative implications on quality of life. These problems are critical as they may have implications for stopping or reducing chemotherapy. All these results call for the development of more research to contribute to the care and wellbeing of people with cancer who receive treatments such as chemotherapy. Thus, this line of research is a new path to be developed by the podiatry community.

摘要

背景

化疗是乳腺癌最常用的治疗方法之一，对人们的生活质量产生了重要影响。然而，针对足部不良反应的研究甚少。本研究旨在确定接受化疗的乳腺癌患者中足部病理的发生情况。

方法

本研究为在西班牙西北部拉科鲁尼亚大学医院肿瘤科进行的观察性、描述性、横断面研究。纳入年龄在 18 岁及以上、正在接受化疗的乳腺癌患者（n=117），并签署了知情同意书。研究了社会人口统计学、合并症、疾病和足部健康变量，以及两个自我管理问卷（足部健康状况问卷和足部功能指数）。本研究遵循了当前的伦理法律要求。

结果

足部健康问题非常普遍，突出表现为指甲变色（59.8%）、甲下血肿（39.7%）、干燥（62.4%）、足底筋膜炎（12.8%）和神经病变症状（75.2%）。77.8%的样本出现了一些足部疼痛，主要位于指甲水平（15.4%）或足底和指甲水平（14.5%）。大多数参与者描述他们的足部健康状况为一般或较差（56.4%），并感到行走受限（65.8%）。足部健康状况问卷的最低分为鞋类（30.6[33.5]）。