Department of Obstetrics & Perinatology, Jagiellonian University Medical College, Cracow, Poland, Poland.
Department of Anaesthesiology and Intensive Therapy, University Hospital in Cracow, Poland, Poland.
Ginekol Pol. 2023;94(10):831-838. doi: 10.5603/gpl.95565. Epub 2023 Aug 21.
The SARS-CoV-2 virus infection has spread to almost all countries in the last two years. Pregnancy complicated with COVID-19 is a unique situation and challenge for doctors. The study aimed to evaluate obstetric results, and biochemical test results and to analyze the treatment used in pregnant patients complicated with COVID-19 infection.
A retrospective analysis of 146 pregnant patients hospitalized at the Department of Obstetrics and Perinatology Jagiellonian University Medical College (JUMC) in Krakow was conducted from July 2020 to August 2021.
In the analyzed group respiratory failure occurred in 19.19% of cases and intravascular coagulation syndrome (DIC) in 1.37%. One patient died (0.68%). 16.6% of cases were transferred to the Intensive Care Unit (ICU) and required intubation. The remaining cases were mild: 39.04% were asymptomatic, 41.78% reported cough, 30.82% dyspnoea and 23.97% myalgia. In the laboratory tests increased values of CRP and IL-6 were observed with normal levels of leukocytes. Additionally, a decreased level of total protein and an increased level of d-dimers were detected. 98.63% of patients received a prophylactic dose of low molecular weight heparin. 46.58% of cases needed additional antibiotic therapy. Cesarean sections were performed in 59.59% of cases. The children were born in good general condition. Vertical transmission of SARS-CoV-2 to the newborn has not been confirmed.
Data from the above study show a significant effect of COVID-19 on pregnant patients. Almost one in five pregnant women occurred respiratory failure and most of them had to be transferred to the ICU department and had to be intubated.
在过去的两年中，SARS-CoV-2 病毒已传播到几乎所有国家。COVID-19 合并妊娠对医生来说是一种独特的情况和挑战。本研究旨在评估合并 COVID-19 感染的孕妇的产科结果、生化检测结果，并分析其治疗方法。
对 2020 年 7 月至 2021 年 8 月在克拉科夫雅盖隆大学医学院妇产科住院的 146 例孕妇进行回顾性分析。
在分析组中，19.19%的病例发生呼吸衰竭，1.37%的病例发生血管内凝血综合征（DIC）。有 1 例患者死亡（0.68%）。16.6%的病例被转至重症监护病房（ICU）并需要插管。其余病例为轻症：39.04%无症状，41.78%咳嗽，30.82%呼吸困难，23.97%肌肉疼痛。在实验室检查中，CRP 和 IL-6 升高，白细胞正常。此外，还检测到总蛋白水平降低和 D-二聚体水平升高。98.63%的患者接受了低分子肝素的预防性剂量。46.58%的病例需要额外的抗生素治疗。59.59%的病例行剖宫产。新生儿出生时一般情况良好。未证实 SARS-CoV-2 垂直传播给新生儿。
上述研究数据表明，COVID-19 对孕妇有显著影响。几乎每五名孕妇中就有一人发生呼吸衰竭，大多数患者需要转至 ICU 部门并进行插管。
