Prieto García Raquel, Millet Joan Pau, Palma David, Barbaglia Navarro María Gabriela, Gibert Cristina Rius
Departament de Ciències Experimentals i de la Salut (DCEXS), Universitat Pompeu Fabra, Barcelona, Spain.
Servei d'Epidemiologia (SEPID), Agència de Salut Pública de Barcelona (ASPB), Barcelona, Spain.
Open Respir Arch. 2023 Jul 4;5(3):100257. doi: 10.1016/j.opresp.2023.100257. eCollection 2023 Jul-Sep.
People who consume drugs have a higher risk of latent tuberculosis infection (LTBI). Our objective was to study the characteristics of people who use drugs and who attended the Centers for Drug Dependence Care and Follow-up of Barcelona during 2017-2021 and presented LTBI or did not perform the reading of the tuberculin skin test (TST) after the test had been done.
A cross-sectional, descriptive study in Centers for Drug Dependence Care and Follow-up of Barcelona was performed during 2017-2021. The sociodemographic and epidemiological profile of people who use drugs that underwent a TST was analyzed and were examined the factors associated with LTBI. Additionally, the same sociodemographic and epidemiological analyses were made in PWUD that did not perform the reading of the TST after the test had been done. Adjusted odds ratios (ORa) and 95% confidence intervals (95% CI) were calculated.
Nine hundred forty-eight persons were profiled. The prevalence of LTBI was 22.9%, and the following factors were associated with it: be older than 41 years; be users of CAS Baluard, or CAS Horta-Guinardó; coming from a WHO region of high TB incidence; be homeless; and low territorial socioeconomic index. The following factors were associated with not performing the reading of the TST after the test had been done: be users from the CAS Baluard, Barceloneta, Nou Barris and Robadors; be homeless and low TSI.
This study improves TB control and highlights the need for this LTBI control program in CASs.
吸毒者患潜伏性结核感染（LTBI）的风险更高。我们的目的是研究2017年至2021年期间在巴塞罗那药物依赖护理与随访中心就诊的吸毒者的特征，这些吸毒者出现了LTBI或在结核菌素皮肤试验（TST）完成后未进行结果读取。
2017年至2021年期间在巴塞罗那药物依赖护理与随访中心进行了一项横断面描述性研究。分析了接受TST的吸毒者的社会人口统计学和流行病学特征，并研究了与LTBI相关的因素。此外，对在TST完成后未进行结果读取的吸毒者进行了相同的社会人口统计学和流行病学分析。计算了调整后的优势比（ORa）和95%置信区间（95%CI）。
共对948人进行了分析。LTBI的患病率为22.9%，与之相关的因素如下：年龄大于41岁；是巴卢阿尔德戒毒中心或霍塔-吉纳尔多戒毒中心的使用者；来自结核病高发病率的世卫组织区域；无家可归；以及地区社会经济指数较低。与在TST完成后未进行结果读取相关的因素如下：是来自巴卢阿尔德戒毒中心、巴塞罗那海滩、新巴里区和罗瓦多斯戒毒中心的使用者；无家可归且TSI较低。
本研究改善了结核病控制，并强调了在戒毒中心实施该LTBI控制项目的必要性。
