Ravi Venkatesh, Winterfield Jeffrey, Liang Jackson, Larsen Timothy, Dye Cicely, Sanders David, Skeete Jamario, Payne Josh, Trohman Richard G, Aksu Tolga, Sharma Parikshit S, Huang Henry D
Saint Francis Heart and Vascular Institute, Tulsa, OK, US.
Department of Cardiology, Medical University of South Carolina, Charleston, SC, US.
Arrhythm Electrophysiol Rev. 2023 Feb 16;12:e04. doi: 10.15420/aer.2022.28. eCollection 2023.
Ventricular tachycardia (VT) is a significant cause of morbidity and mortality in patients with ischaemic and non-ischaemic cardiomyopathies. In most patients, the primary strategy of VT catheter ablation is based on the identification of critical components of reentry circuits and modification of abnormal substrate which can initiate reentry. Despite technological advancements in catheter design and improved ability to localise abnormal substrates, putative circuits and site of origins of ventricular arrhythmias (VAs), current technologies remain inadequate and durable success may be elusive when the critical substrate is deep or near to critical structures that are at risk of collateral damage. In this article, we review the available and potential future non-surgical investigational approaches for treatment of VAs and discuss the viability of these modalities.
室性心动过速（VT）是缺血性和非缺血性心肌病患者发病和死亡的重要原因。在大多数患者中，VT导管消融的主要策略是基于识别折返环路的关键组成部分并改变可引发折返的异常基质。尽管导管设计技术有所进步，定位异常基质、推测的环路以及室性心律失常（VAs）起源部位的能力有所提高，但当关键基质较深或靠近有附带损伤风险的关键结构时，当前技术仍显不足，可能难以实现持久成功。在本文中，我们回顾了现有的以及未来可能用于治疗VAs的非手术研究方法，并讨论这些方法的可行性。
