Sotoodeh Ghorbani Sahar, Taherpour Niloufar, Rahimi Elham, Farhadi Babadi Kosar, Feyzi Rezvan, Hashemi Nazari Seyed Saeed
Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Prevention of Cardiovascular Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2023 Jun 26;37:72. doi: 10.47176/mjiri.37.72. eCollection 2023.
Pregnant women infected with the coronavirus disease 2019 (COVID-19) are at risk for adverse pregnancy outcomes, and the only real preventive strategy against COVID-19 is mass vaccination. This study aimed to examine the effectiveness, immunogenicity, and safety of Covid-19 vaccination in pregnant women.
A combination of search terms was performed by 2 researchers independently in the Web of Science, PubMed, and Scopus databases, the World Health Organization website, and the US Centers for Disease Control (CDC) website up to February 2022. After the selection of eligible studies, the review process, description, and summarization of the selected studies were performed by the research team.
Finally, 22 articles were included in this study. Evidence supports the safety of COVID-19 vaccination during pregnancy. There is no risk of transmitting COVID-19 to infants during lactation. In addition, antibodies made by vaccination can protect infants through breast milk.
The scientific community believes that being vaccinated as soon as possible is the best course of action because there is no evidence to suggest that the COVID-19 vaccine poses a risk to expectant or nursing women.
感染2019冠状病毒病（COVID-19）的孕妇有发生不良妊娠结局的风险，而预防COVID-19的唯一真正有效策略是大规模接种疫苗。本研究旨在探讨孕妇接种COVID-19疫苗的有效性、免疫原性和安全性。
截至2022年2月，两名研究人员独立在科学网、PubMed和Scopus数据库、世界卫生组织网站以及美国疾病控制中心（CDC）网站上进行了搜索词组合检索。在筛选出符合条件的研究后，研究团队对所选研究进行了审查、描述和总结。
最终，本研究纳入了22篇文章。有证据支持孕期接种COVID-19疫苗的安全性。哺乳期不存在将COVID-19传播给婴儿的风险。此外，接种疫苗产生的抗体可通过母乳保护婴儿。
科学界认为，尽快接种疫苗是最佳行动方案，因为没有证据表明COVID-19疫苗会对准妈妈或哺乳期妇女构成风险。
