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High-performance liquid chromatographic method for the determination of proguanil and cycloguanil in biological fluids.

作者信息

Kelly J A, Fletcher K A

出版信息

J Chromatogr. 1986 Sep 5;381(2):464-71. doi: 10.1016/s0378-4347(00)83616-6.

DOI:10.1016/s0378-4347(00)83616-6
PMID:3760104
Abstract
摘要

相似文献

1
High-performance liquid chromatographic method for the determination of proguanil and cycloguanil in biological fluids.高效液相色谱法测定生物体液中的氯胍和环氯胍。
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Simultaneous determination of chloroquine, proguanil and their metabolites in human biological fluids by high-performance liquid chromatography.高效液相色谱法同时测定人体生物体液中的氯喹、氯胍及其代谢产物
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Simultaneous measurement of proguanil and cycloguanil in human plasma by high-performance liquid chromatography.高效液相色谱法同时测定人血浆中的氯胍和环氯胍。
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引用本文的文献

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Single dose pharmacokinetics of proguanil and its metabolites in healthy subjects.健康受试者中氯胍及其代谢产物的单剂量药代动力学
Br J Clin Pharmacol. 1987 Dec;24(6):775-80. doi: 10.1111/j.1365-2125.1987.tb03245.x.
2
Inter-subject variability in the metabolism of proguanil to the active metabolite cycloguanil in man.人体中丙咪嗪代谢为活性代谢物环氯胍的个体间变异性。
Br J Clin Pharmacol. 1989 Jun;27(6):781-7. doi: 10.1111/j.1365-2125.1989.tb03440.x.
3
In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme.
双胍类抗疟药在人肝微粒体中的体外代谢：美芬妥英羟化酶（P450 MP）酶作用的证据。
Br J Clin Pharmacol. 1990 Aug;30(2):287-91. doi: 10.1111/j.1365-2125.1990.tb03777.x.
4
Prevention of malaria.疟疾的预防。
Drugs. 1990 Mar;39(3):337-54. doi: 10.2165/00003495-199039030-00002.