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认知行为社交技能训练:一项针对有精神病风险青少年的随机对照试验结果

Cognitive-Behavioral Social Skills Training: Outcome of a Randomized Controlled Trial for Youth at Risk of Psychosis.

作者信息

Addington Jean, Liu Lu, Braun Amy, Brummitt Kali, Cadenhead Kristin S, Cornblatt Barbara A, Holden Jason L, Granholm Eric

机构信息

Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.

Department of Psychiatry, University of California, San Diego, San Diego, CA, USA.

出版信息

Schizophr Bull Open. 2023 Aug 2;4(1):sgad020. doi: 10.1093/schizbullopen/sgad020. eCollection 2023 Jan.

Abstract

AIM

Difficulties in social functioning have been observed in youth at clinical high-risk (CHR) of psychosis even in those who do not go on to develop a psychotic illness. Few treatment studies have attempted to improve social functioning in this population. The aim of this study was to conduct a randomized trial comparing the effects of Cognitive-Behavioral Social Skills Training (CBSST) with a supportive therapy (ST).

METHODS

Both CBSST and ST were weekly group therapies, delivered over 18 weeks. This was a 2-arm trial with single-blinded ratings and intention-to-treat analyses. Assessments occurred at baseline, end-of-treatment, and 12 months after the baseline assessment. The primary outcome was social and role functioning and defeatist performance attitudes were the secondary outcome. Attenuated positive and negative symptoms, anxiety, depression, self-efficacy, and beliefs about self and others were examined as exploratory outcomes.

RESULTS

There were no significant differences between the 2 groups at baseline or either of the 2 follow-ups. However, at follow-ups, in each group there were significant improvements in clinical symptoms. These could not be attributed to group treatment since there was no control or wait-list group.

CONCLUSIONS

Since poor social functioning is one of the most observed difficulties in CHR individuals, and a decline in social functioning may be a significant predictor of later transition to psychosis, future work will be needed to find effective treatments for this decline in functioning for CHR youth.

摘要

目的

即使在那些未发展为精神病性疾病的临床高危(CHR)青年中,也观察到了社交功能方面的困难。很少有治疗研究试图改善这一人群的社交功能。本研究的目的是进行一项随机试验,比较认知行为社交技能训练(CBSST)与支持性治疗(ST)的效果。

方法

CBSST和ST均为每周一次的团体治疗,为期18周。这是一项双臂试验,采用单盲评分和意向性分析。评估在基线、治疗结束时以及基线评估后12个月进行。主要结局是社交和角色功能,失败主义表现态度是次要结局。对缓解的阳性和阴性症状、焦虑、抑郁、自我效能以及关于自我和他人的信念进行了探索性结局检查。

结果

两组在基线或两次随访中的任何一次均无显著差异。然而,在随访时,每组的临床症状均有显著改善。由于没有对照组或等待名单组,这些改善不能归因于团体治疗。

结论

由于社交功能差是CHR个体中最常见的困难之一,且社交功能下降可能是后期转变为精神病的重要预测因素,因此未来需要开展工作,为CHR青年的这种功能下降找到有效的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc56/11207817/eebf8a789e7b/sgad020_fig1.jpg

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