Attouchi Ikram, Oualha Lamia, Belkacem Chebil Raouaa, Ben Youssef Souha
Oral Medicine and Oral Surgery Department, Sahloul University Hospital, Sousse, Tunisia.
Oral Medicine and Oral Surgery Department, Farhat Hached Hospital, Sousse, Tunisia.
Clin Med Insights Case Rep. 2024 Sep 5;17:11795476241277660. doi: 10.1177/11795476241277660. eCollection 2024.
Calcifying odontogenic cyst, also known as Gorlin cyst is a rare benign cystic lesion primarily found in the jawbones, accounting less than 1% of odontogenic cysts. It can be associated with odontogenic tumors such as odontomas. We report a rare case of COC associated with complex odontoma in a young patient and discuss its clinical features, diagnosis, and treatment options. An 18-year-old female patient presented with a painless radiopaque lesion of the right mandibular bone at Oral Medicine and Oral Surgery department. Radiographs revealed irregular tooth-like structures in the canine-premolar area. The lesion was surgically removed, and histopathology confirmed COC with a complex odontoma. As of the World Health Organization's 2022 definition, COC is a developmental odontogenic cyst characterized by calcified ghost cells. It typically affects individuals during their second and third decades of life, with no gender preference, almost equally in the maxilla and the mandible. The main treatment is total enucleation, with a generally favorable prognosis. Histopathology is essential for diagnosis due to its mimicry of other jaw conditions. Long-term follow-up is needed to prevent recurrences.
钙化性牙源性囊肿，又称戈林囊肿，是一种罕见的良性囊性病变，主要见于颌骨，占牙源性囊肿的比例不到1%。它可与牙源性肿瘤如牙瘤相关。我们报告一例年轻患者中罕见的与复杂牙瘤相关的钙化性牙源性囊肿病例，并讨论其临床特征、诊断和治疗选择。一名18岁女性患者在口腔内科和口腔外科就诊，表现为右下颌骨无痛性不透光病变。X线片显示尖牙-前磨牙区有不规则的牙样结构。病变经手术切除，组织病理学证实为伴有复杂牙瘤的钙化性牙源性囊肿。根据世界卫生组织2022年的定义，钙化性牙源性囊肿是一种以钙化的影细胞为特征的发育性牙源性囊肿。它通常在个体生命的第二个和第三个十年发病，无性别差异，在上颌骨和下颌骨中几乎 equally（此处原文有误，推测应为equally）。主要治疗方法是完全摘除，预后一般良好。由于其可模仿其他颌骨疾病，组织病理学检查对诊断至关重要。需要长期随访以预防复发。
